17β-Dihydro Equilenin 3-Sulfate Sodium Salt

17β-Dihydro Equilenin 3-Sulfate Sodium Salt is chemically Sodium (13S,14S,17S)-17-hydroxy-13-methyl-12,13,14,15,16,17-hexahydro-11H-cyclopenta[a]phenanthren-3-yl sulfate. 17β-Dihydro Equilenin 3-Sulfate Sodium Salt is supplied with detailed characterization data compliant with regulatory guideline. 17β-Dihydro Equilenin 3-Sulfate Sodium Salt can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Equilin.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

The Major Metabolite of Equilin, 4-Hydroxyequilin, Autoxidizes to an o-Quinone Which Isomerizes to the Potent Cytotoxin 4-Hydroxyequilenin-o-quinone
Fagen Zhang, Yumei Chen, Emily Pisha, Li Shen, Yansan Xiong, Richard B. van Breemen, and Judy L. Bolton
Chem. Res. Toxicol. 1999, 12, 204-213
 
HPLC-¯uorescence determination of equilin and equilenin in postmenopausal women's urine
Rita Gatti1 *, Michele Franchina2 , Maria Grazia Gioia1 and Vanni Cavrini1
BIOMEDICAL CHROMATOGRAPHY Biomed. Chromatogr. 14: 82–88 (2000)
 
Quantitative Separation of Free Estrogens by Liquid Partition Chromatography
G. j. krol, R. p. masserano, J. f. carney, and B. t. kho
The United States Pharmacopeia Volume59, Issue10 October 1970 Pages 1483-1487

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