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Nome Químico: (6R,7R)-7-[[(Z)-2-(2-Aminothiazol-4-yl)-2-[(carboxymethoxy)imino]acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid trihydrate (as per EP); (6R,7R)-7-[2-(2-Amino-4-thiazolyl)glyoxylamido]-8-oxo-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 72-(Z)-[O-(carboxymethyl)oxime]trihydrate (as per USP)
Shipping Temperature: Ambient
HSN Code: 38229010
Country of Origin: India
Sorrisos: NC1=NC(/C(C(N[C@]2([H])C(N(C(C(O)=O)=C(C=C)CS3)[C@@]23[H])=O)=O)=N/OCC(O)=O)=CS1
Cefixime Trihydrate is chemically (6R,7R)-7-[[(Z)-2-(2-Aminothiazol-4-yl)-2-[(carboxymethoxy)imino]acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid trihydrate (as per EP); (6R,7R)-7-[2-(2-Amino-4-thiazolyl)glyoxylamido]-8-oxo-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 72-(Z)-[O-(carboxymethyl)oxime]trihydrate (as per USP). Cefixime Trihydrate is supplied with detailed characterization data compliant with regulatory guideline. Cefixime Trihydrate can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cefixime.
The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.
Analytical method development and validation of cefixime and azithromycin by using RP-HPLC
By Sireesha, E.; Reddy, L. Ramachandra; Dhachinamoorthi, D.
From World Journal of Pharmacy and Pharmaceutical Sciences (2019), 8(9), 1160-1177
Stability indicating hplc method for the quantification of cefixime, ornidazole and moxifloxacin in solid dosage forms
By Palacharla, Suresh Kumar; Mohan, G. V. Krishna
From Rasayan Journal of Chemistry (2018), 11(4), 1696-1714
Validated stability-indicating HPTLC method for cefixime and azithromycin with preparative isolation, identification, and characterization of degradation products
By Gawande, V. T.; Bothara, K. G.; Satija, C. O.
From Acta Chromatographica (2018), 30(4), 212-218