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3’-O-Desmethyl Staurosporine

Picture of 3’-O-Desmethyl Staurosporine
SZ CAT No SZ-M063015
CAS No 161743-35-7
Mol.F. C27H24N4O3
Mol.Wt. 452.5
Inv. Status Custom Synthesis


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SynZeal product information given on this website is as per the existing understanding while publishing the details on website. The customer is responsible for assessing the accuracy of the information at the time of actual purchase.

SynZeal will update these details as per new development or finding in product specification without further noticed.

Chemical Name: (5S,6R,7R,9R)-6-hydroxy-5-methyl-7-(methylamino)-6,7,8,9,15,16-hexahydro-5H,14H-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-14-one

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: C[C@@]([C@@H]([C@H](NC)C[C@]1([H])N(C2=CC=CC=C32)C4=C3C5=C6CNC5=O)O)(O1)N7C4=C6C8=CC=CC=C78

3’-O-Desmethyl Staurosporine is chemically (5S,6R,7R,9R)-6-hydroxy-5-methyl-7-(methylamino)-6,7,8,9,15,16-hexahydro-5H,14H-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-14-one. 3’-O-Desmethyl Staurosporine is supplied with detailed characterization data compliant with regulatory guideline. 3’-O-Desmethyl Staurosporine can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Midostaurin.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Impurity profiling and stability-​indicating method development and validation for the estimation of assay and degradation impurities of midostaurin in softgel capsules using HPLC and LC-​MS
By Lakka, Narasimha Swamy; Kuppan, Chandrasekar; Ravinathan, Poornima
From Biomedical Chromatography (2021), Ahead of Print.

RP-​HPLC method development and validation for the estimation of midostaurin in bulk and pharmaceutical dosage form
By Harikrishnan, Narayanaswamy; Subramanian, Gejalakshmi; Hemalatha, C. N.; Pavankumar, V.
From International Journal of Research in Pharmaceutical Sciences (Madurai, India) (2020), 11(4), 5108-5112

Impurity profiling and stability-​indicating method development and validation for the estimation of assay and degradation impurities of midostaurin in softgel capsules using HPLC and LC-​MS
By Lakka Narasimha Swamy; Kuppan Chandrasekar; Ravinathan Poornima
From Biomedical chromatography : BMC (2021), e5222

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