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化学名称: (6R,7R)-7-[[(2R)-2-[[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-[(1E)-prop-1-enyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (as per EP); (6R,7R)-7-{(R)-2-[(R)-2-Amino-2-(4-hydroxyphenyl)acetamido]-2-(4-hydroxyphenyl)acetamido}-8-oxo-3-[(E)-prop-1-enyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (as per USP)
异名: Cefprozil related compound H (E)-isomer ; N-Acyl cefprozil (E-isomer)
Shipping Temperature: Ambient
HSN Code: 38229010
Country of Origin: India
微笑: OC1=CC=C([C@@]([H])(NC([C@]([H])(N)C2=CC=C(O)C=C2)=O)C(N[C@@]3([H])[C@]4([H])N(C3=O)C(C(O)=O)=C(/C=C/C)CS4)=O)C=C1
Cefprozil Monohydrate EP Impurity J is chemically (6R,7R)-7-[[(2R)-2-[[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-[(1E)-prop-1-enyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (as per EP); (6R,7R)-7-{(R)-2-[(R)-2-Amino-2-(4-hydroxyphenyl)acetamido]-2-(4-hydroxyphenyl)acetamido}-8-oxo-3-[(E)-prop-1-enyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (as per USP). It is also known as Cefprozil related compound H (E)-isomer ; N-Acyl cefprozil (E-isomer). Cefprozil Monohydrate EP Impurity J is supplied with detailed characterization data compliant with regulatory guideline. Cefprozil Monohydrate EP Impurity J can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cefprozil Monohydrate.
The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.
Stability indicating methods for the analysis of cefprozil in the presence of its alkaline induced degradation product
By Attia, Khalid A. M.; Nassar, Mohammed W. I.; El-Zeiny, Mohamed B.; Serag, Ahmed
From Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy (2016), 159, 1-6
Spectrophotometric determination of cefepime and cefprozil by three different methods
By Abd El-Sattar, Osama I.; El-Abasawy, N. M.; Abd El-Razeq, S. A.; Ismail, M. M. F.; Rashed, N. S.
From Saudi Pharmaceutical Journal (2001), 9(3-4), 186-191