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化学名称: (8R,9S,13S,14S,17S)-17-([1,1'-Biphenyl]-4-yl)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
Shipping Temperature: Ambient
HSN Code: 38229010
Country of Origin: India
微笑: C[C@@]1([C@](O)(C2=CC=C(C3=CC=CC=C3)C=C2)CC4)[C@]4([H])[C@]5([H])CCC6=CC(O)=CC=C6[C@@]5([H])CC1
Equilenin Impurity 1 is chemically (8R,9S,13S,14S,17S)-17-([1,1'-Biphenyl]-4-yl)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol. Equilenin Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. Equilenin Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Equilenin.
The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.
Formation of equilenin from equilin by porcine adrenals
K. L. Cheo and K. H. Loke
Steroids Volume 11, Issue 5, May 1968, Pages 603-608
The Major Metabolite of Equilin, 4-Hydroxyequilin, Autoxidizes to an o-Quinone Which Isomerizes to the Potent Cytotoxin 4-Hydroxyequilenin-o-quinone
Fagen Zhang, Yumei Chen, Emily Pisha, Li Shen, Yansan Xiong, Richard B. van Breemen, and Judy L. Bolton
Chem. Res. Toxicol. 1999, 12, 204-213
