Levofloxacin EP Impurity I 

Levofloxacin EP Impurity I  is chemically (3S)-10-fluoro-3-methyl-9-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid. It is also known as Levofloxacin 9-Piperazinyl Isomer ; 10-Fluoro Impurity. Levofloxacin EP Impurity I  is supplied with detailed characterization data compliant with regulatory guideline. Levofloxacin EP Impurity I  can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Levofloxacin.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

In silico and in vitro genotoxicity evaluation of levofloxacin n-oxide, an impurity in levofloxacin
Qingfen Zhu1,2, Tao Li2 , Jun Li2 , Ming Guo2 , Weijian Wang2 , and Xiumei Zhang
Toxicology Mechanisms and Methods, 2012; 22(3): 225–230
 
Identification, Isolation and Characterization of New Process-related Impurities in Levofloxacin
Kishor More* , Leena Gupta, Brajesh Sharma, Prashant Patil, Dattatray Govare
Der Pharma Chemica, 2017, 9(12):7-13
 
An integrated approach for detection and characterization of the trace impurities in levofloxacin using liquid chromatography– tandem mass spectrometry
Ya-Jie Zheng1 , Jiu-Ming He1 , Rui-Ping Zhang1 , Yu-Cheng Wang2 , Ju-Xian Wang2 , Hui-Qing Wang1 , Yan Wu1 , Wen-Yi He1 and Zeper Abliz
Rapid Commun. Mass Spectrom. 2014, 28, 1164–1174
 
Analyses of Levofloxacin Adsorption on Pretreated Barley Straw with Respect to Temperature: Kinetics, π–π Electron-Donor–Acceptor Interaction and Site Energy Distribution
Bei Yan, Catherine Hui Niu, and Jian Wang
Environ. Sci. Technol. 2017, 51, 14, 8048–8056
 
Rapid chiral separation and impurity determination of levofloxacin by ligand-exchange chromatography
Hongyuan Yan, Kyung Ho Row
Analytica Chimica Acta 584 (2007) 160–165

• We need to receive valid purchase order with Bill to & Ship to address.
• The quotation ID needs to be mentioned in the purchase order.
• You will receive order confirmation prior to dispatch which need to be verified for any error in product, pack size, prices.

Delivery time:

• In Stock product will dispatch in 24 h after receipt of purchase order. It usually take 2-3 days to receive products in India and 5-6 working days for export customer depending on destination.
• The custom synthesis products would be dispatched as per quoted timeline.

Shipping:

• There will be 100 USD towards logistic charges per shipment if we used our FedEx. There will not be any charge if we use your FedEx/DHL Account. Depending on part shipment logistic charges will be added.
• For countries dispatch by courier is not allowed where product would be dispatched in cargo mode as per agreed Inco term.

Additional Charges:

• Controlled substance charges need to follow as per quotation. The specific inputs are required for controlled substance because regulatory status will differ based on destination.
• Cold Shipment Charges needs to be considered as per quotation.
• For ice pack there are no additional charges.

Technical Queries:

• All technical queries need to raise within 15 days of product receipt. Thereafter it will be our resolved at our discretion.

Reach to Us:

• All communication will be addressed to standards@synzeal.com
• SynZeal emphasize on formal communication which is required for smooth processing of the purchase order. It helps multiple people to remain informed about all details.
• For specific purpose, there are below e-mail address to be used.
  • For New products # standards@synzeal.com
  • Order confirmation # order@synzeal.com
  • Open Order Status # projects@synzeal.com
  • Data related Query # support@synzeal.com
  • Invoice Related Query # sales@synzeal.com
  • Logistic Documents # exports@synzeal.com (For export customer only)
• It is recommended to include standards@synzeal.com always in CC while communicating to other e-mail address.
• SynZeal is committed for promptly responding all communication however if sometime urgent comes us you can use our WhatsApp customer care channel (+91 70690 37751) to reach to customer support team. You can also request call back on WhatsApp and our customer support team will reach to you in defined timeframe.