(R)-Ofloxacin Carboxylic Acid

(R)-Ofloxacin Carboxylic Acid is chemically (R)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid. It is also known as Dextrofloxacin Difluoro Impurity. (R)-Ofloxacin Carboxylic Acid is supplied with detailed characterization data compliant with regulatory guideline. (R)-Ofloxacin Carboxylic Acid can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ofloxacin.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Use of various β-cyclodextrin derivatives as chiral selectors for the enantiomeric separation of ofloxacin and its five related substances by capillary electrophoresis
Bolin Zhu , Shuying Xu , Xingjie Guo , Lan Wei , Jia Yu , Tiejie Wang
J Sep Sci. 2017 Apr;40(8):1784-1795.
 
Stability Indicating Reversed-Phase High Performance Liquid Chromatography Method for Determination of Impurities in Ofloxacin Tablet Formulations
Bobba Venkateswara Reddy,1 Avvaru Praveen Kumar,2 Gosula Venkat Ram Reddy,1 Mohinish Sahai,1 Jadi Sreeramulu,1 and Jung Hag Park
Analytical Letters, 43: 2653–2662, 2010
 
Enantioseparation of ofloxacin and its four related substances with ligand exchange–micellar electrokinetic chromatography using copper(II)‐L‐isoleucine complex as chiral selector
Yongjing Liu  Xiaoying Wang
Chirality Volume29, Issue8 August 2017 Pages 422-429
 
Multiple Response Optimization of a HPLC Method for the Determination of Enantiomeric Purity of S-Ofloxacin
Valliappan Kannappan & Sai Sandeep Mannemala
Chromatographia volume 77, pages1203–1211(2014)

• We need to receive valid purchase order with Bill to & Ship to address.
• The quotation ID needs to be mentioned in the purchase order.
• You will receive order confirmation prior to dispatch which need to be verified for any error in product, pack size, prices.

Delivery time:

• In Stock product will dispatch in 24 h after receipt of purchase order. It usually take 2-3 days to receive products in India and 5-6 working days for export customer depending on destination.
• The custom synthesis products would be dispatched as per quoted timeline.

Shipping:

• There will be 100 USD towards logistic charges per shipment if we used our FedEx. There will not be any charge if we use your FedEx/DHL Account. Depending on part shipment logistic charges will be added.
• For countries dispatch by courier is not allowed where product would be dispatched in cargo mode as per agreed Inco term.

Additional Charges:

• Controlled substance charges need to follow as per quotation. The specific inputs are required for controlled substance because regulatory status will differ based on destination.
• Cold Shipment Charges needs to be considered as per quotation.
• For ice pack there are no additional charges.

Technical Queries:

• All technical queries need to raise within 15 days of product receipt. Thereafter it will be our resolved at our discretion.

Reach to Us:

• All communication will be addressed to standards@synzeal.com
• SynZeal emphasize on formal communication which is required for smooth processing of the purchase order. It helps multiple people to remain informed about all details.
• For specific purpose, there are below e-mail address to be used.
  • For New products # standards@synzeal.com
  • Order confirmation # order@synzeal.com
  • Open Order Status # projects@synzeal.com
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  • Invoice Related Query # sales@synzeal.com
  • Logistic Documents # exports@synzeal.com (For export customer only)
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