Venlafaxine Anhydro O-Desmethyl Impurity

Venlafaxine Anhydro O-Desmethyl Impurity is chemically 4-[1-(Cyclohex-1-en-1-yl)-2-(dimethylamino)ethyl]phenol. It is also known as Desvenlafaxine USP Related Compound A ; Desvenlafaxine Anhydro Impurity. Venlafaxine Anhydro O-Desmethyl Impurity is supplied with detailed characterization data compliant with regulatory guideline. Venlafaxine Anhydro O-Desmethyl Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Venlafaxine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

An Improved and Impurity-Free Large-Scale Synthesis of Venlafaxine Hydrochloride
Mohanarangam Saravanan, Bollikonda Satyanarayana, and Padi Pratap Reddy
Org. Process Res. Dev. 2011, 15, 6, 1392–1395
 
Simultaneous stereoselective analysis of venlafaxine and O-desmethylvenlafaxine enantiomers in clinical samples by capillary electrophoresis using charged cyclodextrins
Serge Rudaz, Cinzia Stella, Androniki E Balant-Gorgia, Salvatore Fanali, Jean-Luc Veuthey
Journal of Pharmaceutical and Biomedical Analysis Volume 23, Issue 1, 1 August 2000, Pages 107-115

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