Acrivastine Impurity 4

Development and validation of a rapid stability indicating HPLC-​method using monolithic stationary phase and two spectrophotometric methods for determination of antihistaminic acrivastine in capsules
By Gouda, Ayman A.; Hashem, Hisham; Jira, Thomas
From Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy (2014), 130, 480-487

Acrivastine Impurity 4 is chemically (E)-3-(6-(1-hydroxy-3-(pyrrolidin-1-yl)-1-(p-tolyl)propyl)pyridin-2-yl)acrylic acid. Acrivastine Impurity 4 is supplied with detailed characterization data compliant with regulatory guideline. Acrivastine Impurity 4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Acrivastine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.