Apalutamide Impurity 17

Apalutamide Impurity 17 is chemically 2-Fluoro-1-methyl-4-nitrobenzene. Apalutamide Impurity 17 is supplied with detailed characterization data compliant with regulatory guideline. Apalutamide Impurity 17 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Apalutamide.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Structure-Activity Relationship for Thiohydantoin Androgen Receptor Antagonists for Castration-Resistant Prostate Cancer (CRPC)
Michael E. Jung,*,† Samedy Ouk,† Dongwon Yoo,† Charles L. Sawyers,‡,§ Charlie Chen,‡ Chris Tran,‡ and John Wongvipat
J. Med. Chem. 2010, 53, 2779–2796
 
Review of Synthetic Routes and Crystalline Forms of the Antiandrogen Oncology Drugs Enzalutamide, Apalutamide, and Darolutamide
David L. Hughes*
Org. Process Res. Dev. 2020, 24, 3, 347–362
 
Discovery of deshydroxy bicalutamide derivatives as androgen receptor antagonists
S. Kandil, K.Y. Lee, L. Davies, S.A. Rizzo, D.A. Dart, A.D. Westwell, Discovery of deshydroxy bicalutamide derivatives as androgen receptor antagonists, European Journal of Medicinal Chemistry (2019)
European Journal of Medicinal Chemistry Volume 167, 1 April 2019, Pages 49-60

• We need to receive valid purchase order with Bill to & Ship to address.
• The quotation ID needs to be mentioned in the purchase order.
• You will receive order confirmation prior to dispatch which need to be verified for any error in product, pack size, prices.

Delivery time:

• In Stock product will dispatch in 24 h after receipt of purchase order. It usually take 2-3 days to receive products in India and 5-6 working days for export customer depending on destination.
• The custom synthesis products would be dispatched as per quoted timeline.

Shipping:

• There will be 100 USD towards logistic charges per shipment if we used our FedEx. There will not be any charge if we use your FedEx/DHL Account. Depending on part shipment logistic charges will be added.
• For countries dispatch by courier is not allowed where product would be dispatched in cargo mode as per agreed Inco term.

Additional Charges:

• Controlled substance charges need to follow as per quotation. The specific inputs are required for controlled substance because regulatory status will differ based on destination.
• Cold Shipment Charges needs to be considered as per quotation.
• For ice pack there are no additional charges.

Technical Queries:

• All technical queries need to raise within 15 days of product receipt. Thereafter it will be our resolved at our discretion.

Reach to Us:

• All communication will be addressed to standards@synzeal.com
• SynZeal emphasize on formal communication which is required for smooth processing of the purchase order. It helps multiple people to remain informed about all details.
• For specific purpose, there are below e-mail address to be used.
  • For New products # standards@synzeal.com
  • Order confirmation # order@synzeal.com
  • Open Order Status # projects@synzeal.com
  • Data related Query # support@synzeal.com
  • Invoice Related Query # sales@synzeal.com
  • Logistic Documents # exports@synzeal.com (For export customer only)
• It is recommended to include standards@synzeal.com always in CC while communicating to other e-mail address.
• SynZeal is committed for promptly responding all communication however if sometime urgent comes us you can use our WhatsApp customer care channel (+91 70690 37751) to reach to customer support team. You can also request call back on WhatsApp and our customer support team will reach to you in defined timeframe.