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Chemical Name: 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl] amino](4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H- tetrazol-5-yl)thio]methyl]-8-oxo-, [6R-[6alpha,7beta (R*)]]-, dihydrate (as per USP)
Synonym: Biocefazon
Shipping Temperature: Ambient
HSN Code: 38229010
Country of Origin: India
Smiles: OC(C(N1[C@@]2([H])[C@H](NC([C@@H](C3=CC=C(O)C=C3)NC(N(CCN(CC)C4=O)C4=O)=O)=O)C1=O)=C(CS2)CSC5=NN=NN5C)=O.[2H2O]
Cefoperazone Dihydrate is chemically 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl] amino](4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H- tetrazol-5-yl)thio]methyl]-8-oxo-, [6R-[6alpha,7beta (R*)]]-, dihydrate (as per USP). It is also known as Biocefazon. Cefoperazone Dihydrate is supplied with detailed characterization data compliant with regulatory guideline. Cefoperazone Dihydrate can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cefoperazone.
The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.
Development and Validation of Stability Indicating HPLC Method for the Determination of Impurities in the Sterile Mixture of Cefoperazone and Sulbactam
By Ivaturi, Ramu; Sastry, Thuttagunta Manikya; Sunkara, Satyaveni
From Current Pharmaceutical Analysis (2019), 15(7), 762-775
Stability indicating method development and validation for simultaneous estimation of cefoperazone and tazobactam by using RP-HPLC
By Vytla, Sri Viswa Madhuri; Prasad, S. V. U. M.; Kuna, Mangamma
From Indo American Journal of Pharmaceutical Sciences (2017), 4(7), 2195-2203
Development and validation of HPLC and HPTLC methods for determination of cefoperazone and its related impurities
By Abdelaleem, Eglal A.; Naguib, Ibrahim A.; Zaazaa, Hala E.; Hussein, Essraa A.
From Journal of Chromatographic Science (2016), 54(2), 179-186