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Velpatasvir Diastereomer 3

Picture of Velpatasvir Diastereomer 3
SZ CAT No SZ-V013004
CAS No NA
Mol.F. C49H54N8O8
Mol.Wt. 883.0
Inv. Status Under Synthesis


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Chemical Name: Methyl ((R)-2-((2R,4S)-2-(5-(2-((2S,5S)-1-((methoxycarbonyl)-L-valyl)-5-methylpyrrolidin-2-yl)-1,11-dihydroisochromeno[4',3':6,7]naphtho[1,2-d]imidazol-9-yl)-1H-imidazol-2-yl)-4-(methoxymethyl)pyrrolidin-1-yl)-2-oxo-1-phenylethyl)carbamate

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: COC[C@H]1C[C@H](C2=NC=C(C3=CC4=C(C5=CC6=CC=C7C(NC([C@H]8N(C([C@@H](NC(OC)=O)C(C)C)=O)[C@@H](C)CC8)=N7)=C6C=C5OC4)C=C3)N2)N(C([C@H](NC(OC)=O)C9=CC=CC=C9)=O)C1

Velpatasvir Diastereomer 3 is chemically Methyl ((R)-2-((2R,4S)-2-(5-(2-((2S,5S)-1-((methoxycarbonyl)-L-valyl)-5-methylpyrrolidin-2-yl)-1,11-dihydroisochromeno[4',3':6,7]naphtho[1,2-d]imidazol-9-yl)-1H-imidazol-2-yl)-4-(methoxymethyl)pyrrolidin-1-yl)-2-oxo-1-phenylethyl)carbamate. Velpatasvir Diastereomer 3 is supplied with detailed characterization data compliant with regulatory guideline. Velpatasvir Diastereomer 3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Velpatasvir.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

UPLC Separation of forced degradation and process related impurities of Velpatasvir and structure elucidation by online LC-Quadrupole-Time of flight-Tandem mass Spectrometry
Md. Sattar Abdul*, Suneetha A.Research Journal of Pharmacy and Technology
Year : 2019, Volume : 12, Issue : 2
First page : ( 477) Last page : ( 482)

Stability indicating RP-HPLC Method development and Validation for the Estimation of Sofosbuvir, Velpatasvir and Voxilaprevir in Bulk and Pharmaceutical dosage form
Kokkirala, Tej Kumar; Suryakala, Duvvuri. Research Journal of Pharmacy and Technology; RaipurVol. 13, Iss. 11, (Nov 2020): 5063-5071. DOI:10.5958/0974-360X.2020.00887.2

RP-HPLC Method Development and Validation for Velpatasvir and Voxilaprevir by Simultaneous Determination in Bulk and Their Pharmaceutical Dosage Forms
DebasishSwainaAmrej SinghYadavaChandrasekharSasapuaVenkatakrishnaAkulabGananadhamuSamanthulaa
Microchemical JournalVolume 155, June 2020, 104657

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