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Nome Químico: (1′S,6′R)-7-Chloro-2′,4,6-trimethoxy-6′-methyl-3H-spiro[1-benzofuran-2,1′-cyclohex[2]ene]-3,4′-dione (as per EP)
Sinônimo: Amudane ; Sporostatin ; Xuanjing
Shipping Temperature: Ambient
HSN Code: 38229010
Country of Origin: India
Sorrisos: O=C(C=C1OC)C[C@@H](C)[C@@]21OC3=C(Cl)C(OC)=CC(OC)=C3C2=O
Griseofulvin is chemically (1′S,6′R)-7-Chloro-2′,4,6-trimethoxy-6′-methyl-3H-spiro[1-benzofuran-2,1′-cyclohex[2]ene]-3,4′-dione (as per EP). It is also known as Amudane ; Sporostatin ; Xuanjing. Griseofulvin is supplied with detailed characterization data compliant with regulatory guideline. Griseofulvin can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Griseofulvin.
The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.
Development and validation of a reversed phase liquid chromatographic method for analysis of griseofulvin and impurities
Getu Kahsaya, Aremu Olajire Adegoke b, Ann Van Schepdael a, Erwin Adams
Journal of Pharmaceutical and Biomedical Analysis 80 (2013) 9–17
Thermodynamics, Molecular Mobility and Crystallization Kinetics of Amorphous Griseofulvin
Deliang Zhou,Geoff G. Z. Zhang, Devalina Law,David J. W. Grant, and Eric A. Schmitt
Mol. Pharmaceutics 2008, 5, 6, 927–936
In Vitro additive effect on griseofulvin and terbinafine combinations against multidrug-resistant dermatophytes
Aline Jacobi Dalla Lana, Bruna Pippi, Anderson Ramos Carvalho, Renata Cougo Moraes, Samuel Kaiser, George Gonzalez Ortega, Alexandre Meneghello Fuentefria, Gustavo Pozza Silveira
Braz. J. Pharm. Sci. vol.54 no.2 São Paulo 2018 Epub July 26, 2018