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化学名称: (2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentaol hemi((3-(((2R,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate)
Shipping Temperature: Ambient
HSN Code: 38229010
Country of Origin: India
微笑: O=P(O)(N1N=C(CN2[C@@H](C3=CC=C(F)C=C3)[C@@H](O[C@@H](C)C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)OCC2)NC1=O)O.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
Fosaprepitant Dimeglumine Impurity D is chemically (2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentaol hemi((3-(((2R,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate). Fosaprepitant Dimeglumine Impurity D is supplied with detailed characterization data compliant with regulatory guideline. Fosaprepitant Dimeglumine Impurity D can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Fosaprepitant.
The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.
GC-FID technique for the quantitative evaluation of multiple residual organic solvent impurities in fosaprepitant dimeglumine drug
By Reddy, H. Ramakrishna; Pratap, S. R.; Chandrasekhar, N.; Shamshuddin, S. Z. M.
From Asian Journal of Chemistry (2021), 33(7), 1645-1650
Quantification and method validation of dicyclohexylurea content in fosaprepitant dimeglumine drug substance by reverse phase HPLC
By Kishore, M. V.; Sivarao, T.; Srinivas, K. Rama; Satyendranath, Ch. V.; Kumar, Vundavilli Jagadeesh; Kumar, K. S. R. Pavan; Sreenivas, N.
From International Journal of Pharmaceutical Sciences and Research (2020), 11(10), 5010-5016
Quality by design approach for development and validation of stability indicating RP-HPLC method for fosaprepitant dimeglumine
By Shaikh, Jalil K.; Farooqui, Mazahar; Syed, Ummul Khair Asema
From Asian Journal of Chemistry (2020), 32(9), 2158-2164
