Trazodone EP Impurity A

Trazodone EP Impurity A is chemically 4-(3-chlorophenyl)-1-[3-(3-oxo-2,3-dihydro[1,2,4]triazolo[4,3-a]pyridin-2-yl)propyl]piperazine 1-oxide (as per EP) ; 4-(3-Chlorophenyl)-1-[3-(3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2(3H)-yl)propyl]piperazine 1-oxide (as per USP). It is also known as Trazodone N-Oxide (USP). Trazodone EP Impurity A is supplied with detailed characterization data compliant with regulatory guideline. Trazodone EP Impurity A can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Trazodone.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

The investigation of electrospun polymer nanofibers as a solid-phase extraction sorbent for the determination of trazodone in human plasma
Xuejun Kang, Cao Pan, Qian Xua, Yingfang Yao, Yian Wang, Dongjin Qi, Zhongze Gu
Analytica Chimica Acta Volume 587, Issue 1, 21 March 2007, Pages 75-81
 
Liquid Chromatographic Methods for Determination of Trazodone and Related Compounds in Drug Raw Materials
Normand Beaulieu, Roger W Sears, Edward G Lovering
Journal of aoac international, Volume 77, Issue 4, 1 July 1994, Pages 857–861
 
Application of the UHPLC method for separation and characterization of major photolytic degradation products of trazodone by LC-MS and NMR
Mohit Thummar,  Prinesh N. Patel, Bhoopendra Singh Kushwaha  and  Gananadhamu Samanthula
New J. Chem., 2018,42, 16972-16984

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• In Stock product will dispatch in 24 h after receipt of purchase order. It usually take 2-3 days to receive products in India and 5-6 working days for export customer depending on destination.
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