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Search Results for " Abemaciclib "

Picture of Abemaciclib N-Oxide Impurity 3

Abemaciclib N-Oxide Impurity 3

SZ CAT No:SZ-A077032
CAS NoNA
Mol.F.C27H32F2N8O
Mol.Wt.522.6
Inv. StatusCustom Synthesis

Chemical Name: 5-((4-Ethylpiperazin-1-yl)methyl)-2-((5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)amino)pyridine 1-oxide

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: CC1=NC2=C(F)C=C(C3=NC(NC4=CC=C(CN5CCN(CC)CC5)C=[N+]4[O-])=NC=C3F)C=C2N1C(C)C

Development and validation of a bioanalytical method for the quantification of the CDK4​/6 inhibitors abemaciclib, palbociclib, and ribociclib in human and mouse matrices using liquid chromatography-​tandem mass spectrometry
By Martinez-Chavez, Alejandra; Rosing, Hilde; Hillebrand, Michel; Tibben, Matthijs; Schinkel, Alfred H.; Beijnen, Jos H.
From Analytical and Bioanalytical Chemistry (2019), 411(20), 5331-5345

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