SynZeal product information given on this website is as per the existing understanding while publishing the details on website. The customer is responsible for assessing the accuracy of the information at the time of actual purchase.
SynZeal will update these details as per new development or finding in product specification without further noticed.
Chemical Name: (8S,9R,10S,11S,13S,14S,16R,17R)-9-Fluoro-3',11-dihydroxy-10,13,16-trimethyl-7,8,9,10,11,12,13,14,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,2'-oxet]-3(6H)-one
Shipping Temperature: Ambient
HSN Code: 38229010
Country of Origin: India
Smiles: C[C@@]12[C@@]3(C(O)=CO3)[C@H](C)C[C@@]1([H])[C@]4([H])CCC5=CC(C=C[C@]5(C)[C@@]4(F)[C@@H](O)C2)=O
Clobetasol Propionate Impurity 1 is chemically (8S,9R,10S,11S,13S,14S,16R,17R)-9-Fluoro-3',11-dihydroxy-10,13,16-trimethyl-7,8,9,10,11,12,13,14,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,2'-oxet]-3(6H)-one. Clobetasol Propionate Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. Clobetasol Propionate Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Clobetasol Propionate.
The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.
Development and validation of a fast RP-HPLC method for the determination of clobetasol propionate in topical nanocapsule suspensions
By Fontana M C; Bastos M O; Beck R C R
From Journal of chromatographic science (2010), 48(8), 637-40
Qualitative and quantitative assessment of related substances in the Compound Ketoconazole and Clobetasol Propionate Cream by HPLC-TOF-MS and HPLC
By Yang Wenling; Yang Xiaomei; Shi Fanghua; Wang Ruixun; Li Qing; Bi Kaishun; Liao Zhigang; Liang Yongkun; Yu Liangzhong
From Journal of pharmaceutical analysis (2019), 9(3), 156-162