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Dihydronarwedine

SZ CAT No SZ-G002009
CAS No 21041-10-1
Mol.F. C17H21NO3
Mol.Wt. 287.3
Inv. Status In Stock


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SynZeal product information given on this website is as per the existing understanding while publishing the details on website. The customer is responsible for assessing the accuracy of the information at the time of actual purchase.

SynZeal will update these details as per new development or finding in product specification without further noticed.

Chemical Name: (4aS,8aR)-4a,5,7,8,9,10,11,12-Octahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-one; 3-Deoxy-1,2-dihydro-3-oxo-galanthamine; 2-Deoxy-2-oxo-lycoramine; Deoxyoxo-lycoramine; 6H-Benzofuro[3a,3,2-ef][2]benzazepine, (-)-Dihydrogalanthaminone; (-)-Lycoraminone; 1,2-Dihydro Galanthaminone

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: COC1=CC=C(CN(CC2)C)C3=C1O[C@@H]4[C@@]32CCC(C4)=O

Dihydronarwedine is chemically (4aS,8aR)-4a,5,7,8,9,10,11,12-Octahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-one; 3-Deoxy-1,2-dihydro-3-oxo-galanthamine; 2-Deoxy-2-oxo-lycoramine; Deoxyoxo-lycoramine; 6H-Benzofuro[3a,3,2-ef][2]benzazepine, (-)-Dihydrogalanthaminone; (-)-Lycoraminone; 1,2-Dihydro Galanthaminone. Dihydronarwedine is supplied with detailed characterization data compliant with regulatory guideline. Dihydronarwedine can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Galantamine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Development of a Novel High-Concentration Galantamine Formulation Suitable for Intranasal Delivery
Alexis kays leonard, anthony p. sileno, conor macevilly, charles a. foerder, steven c. quay, henry r. costantino
Journal of pharmaceutical sciences, vol. 94, no. 8, august 2005 pages 1736-1746
 
Methods for the analysis of galanthamine and its extraction from laboratory to industrial scale
Muhammad Nadeem Akramab Robert Verpoortea Barbora Pomahačová
South African Journal of Botany Volume 136, January 2021, Pages 51-64
 
Determination of galantamine hydrobromide in bulk drug and pharmaceutical dosage form by spectrofluorimetry
Amit V. Patel, Vishal J. Patel, Avani V. Patel, Jayant B. Dave, Chhaganbhai N. Patel
J Pharm Bioallied Sci. 2013 Oct-Dec; 5(4): 314–317
 
Quantitative analysis of drugs in biological matrices by HPLC hyphenated to fluorescence detection
Emmanuelle Lipka & Claude Vaccher
Bioanalysis (2015) 7(6), 743–762

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