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Hyoscine Butylbromide-d9

SZ CAT No SZ-H013D01
CAS No NA
Mol.F. C21H21D9NO4 : Br
Mol.Wt. 369.5 : 79.9
Inv. Status Custom Synthesis
Rel. CAS No 149-64-4 (Unlabelled)


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SynZeal will update these details as per new development or finding in product specification without further noticed.

Chemical Name: (1R,2R,4S,5S,7s,9S)-9-(Butyl-d9)-7-(((S)-3-hydroxy-2-phenylpropanoyl)oxy)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-9-ium bromide

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C(O[C@@]1(C[C@]([N@@+]2(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])C)([H])[C@@]([H])(O3)[C@]3([H])[C@]2([H])C1)[H])[C@]([H])(CO)C4=CC=CC=C4.[Br-]

Hyoscine Butylbromide-d9 is chemically (1R,2R,4S,5S,7s,9S)-9-(Butyl-d9)-7-(((S)-3-hydroxy-2-phenylpropanoyl)oxy)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-9-ium bromide. Hyoscine Butylbromide-d9 is supplied with detailed characterization data compliant with regulatory guideline. Hyoscine Butylbromide-d9 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Hyoscine Butylbromide.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

LC-MS as a Stability-Indicating Method for Analysis of Hyoscine N-Butyl Bromide under Stress Degradation Conditions with Identification of Degradation Products
Nouruddin W Ali , Mohammed Gamal1 * and Mohammed Abdelkawy
Ali et al., Pharm Anal Acta 2013, S7
 
Simultaneous determination of hyoscine N-butyl bromide and paracetamol in their binary mixture by RP-HPLC method
Nouruddin W. Ali  Mohammed Gamal ,Mohammed Abdelkawy
Arabian Journal of Chemistry Volume 10, Supplement 2, May 2017, Pages S1868-S1874
 
The effect of hyoscine butylbromide in shortening the first stage of labor: A double blind, randomized, controlled, clinical trial
Nourah H Al Qahtani1 and Fatma Al Hajeri2
Ther Clin Risk Manag. 2011; 7: 495–500.

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