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Chemical Name: N,N,α-Trimethyl-10H-phenothiazine-10-ethanamine N-Oxide
Shipping Temperature: Ambient
HSN Code: 38229010
Country of Origin: India
Smiles: CC([N](C)(C)=O)CN1C(C=CC=C2)=C2SC3=CC=CC=C13
Promethazine N-Oxide is chemically N,N,α-Trimethyl-10H-phenothiazine-10-ethanamine N-Oxide. Promethazine N-Oxide is supplied with detailed characterization data compliant with regulatory guideline. Promethazine N-Oxide can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Promethazine.
The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.
Chromatographic determination of promethazine hydrochloride in aqueous solution
B. J. Meakin, D. J. G. Davies, Norma Cox and John Stevens
Analyst, 1976,101, 720-727
Determination of thiazinamium, promazine and promethazine in pharmaceutical formulations using a CZE method
Francisco J. Lara, Ana M. Garc´ıa-Campana˜ ∗, Ferm´ın Ales-Barrero, ´ Juan M. Bosque-Sendra
Analytica Chimica Acta Volume 535, Issues 1–2, 11 April 2005, Pages 101-108
Stability Indicating RP-HPLC Method Development for Related Substances of Anti-Histamine Promethazine Hydrochloride and its Validation Study.
Nilesh Takale, Neelakandan Kaliyaperumal, Gopal Krishnan, Mannathusamy and Raja Rajan Govindasamy
Orient. J. Chem., Vol. 36(5), 889-896 (2020)
Identification and determination of ketotifen hydrogen fumarate, azelastine hydrochloride, dimetindene maleate and promethazine hydrochloride by densitometric method.
Wyszomirska E1, Czerwińska K1, Kublin E1, Mazurek AP1
Acta Poloniae Pharmaceutica, 01 Nov 2013, 70(6):951-959