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2’,7,10- Tri-cis-aconityl Docetaxel

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N° de SZ CAT SZ-D031051
Número CAS NA
Mol.F. C61H59NO26
Peso Molecular 1222.1
Status de Fatura Custom Synthesis


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SynZeal product information given on this website is as per the existing understanding while publishing the details on website. The customer is responsible for assessing the accuracy of the information at the time of actual purchase.

SynZeal will update these details as per new development or finding in product specification without further noticed.

Nome Químico: (2aR,4S,4aS,6R,9S,11S,12S,12bS)-12b-acetoxy-12-(benzoyloxy)-9-(((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-(2-(2,5-dioxo-2,5-dihydrofuran-3-yl)acetoxy)-3-phenylpropanoyl)oxy)-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-4,6-diyl bis(2-(2,5-dioxo-2,5-dihydrofuran-3-yl)acetate)

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Sorrisos: CC1(C)[C@@]2(O)C[C@H](OC([C@H](OC(CC3=CC(OC3=O)=O)=O)[C@H](C4=CC=CC=C4)NC(OC(C)(C)C)=O)=O)C(C)=C1[C@@H](OC(CC(C(O5)=O)=CC5=O)=O)C([C@@]6(C)C([C@@H]2OC(C7=CC=CC=C7)=O)[C@@](CO8)(OC(C)=O)[C@H]8C[C@@H]6OC(CC9=CC(OC9=O)=O)=O)=O

2’,7,10- Tri-cis-aconityl Docetaxel is chemically (2aR,4S,4aS,6R,9S,11S,12S,12bS)-12b-acetoxy-12-(benzoyloxy)-9-(((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-(2-(2,5-dioxo-2,5-dihydrofuran-3-yl)acetoxy)-3-phenylpropanoyl)oxy)-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-4,6-diyl bis(2-(2,5-dioxo-2,5-dihydrofuran-3-yl)acetate). 2’,7,10- Tri-cis-aconityl Docetaxel is supplied with detailed characterization data compliant with regulatory guideline. 2’,7,10- Tri-cis-aconityl Docetaxel can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Docetaxel.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Development and validation of RP-​HPLC method for simultaneous estimation of docetaxel and ritonavir in PLGA nanoparticles
Quick View Other Sources
By Kumbhar, P. S.; Diwate, Sonali K.; Mali, U. G.; Shinde, T. U.; Disouza, J. I.; Manjappa, A. S.
From Annales Pharmaceutiques Francaises (2020), 78(5), 398-407
 

 

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