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Atracurium cis-Quaternary Acid

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N° de SZ CAT SZ-A021060
Número CAS 1075727-06-8
Mol.F. C24H32NO6 : C6H5O3S
Peso Molecular 430.5 : 157.2
Status de Fatura In Stock
Rel. CAS No 1075727-04-6 (free base) ; 1075727-07-9 (Iodide salt)
Rel. CAT No SZ-A021004, SZ-C130002, SZ-C130028,


Disclaimer

SynZeal product information given on this website is as per the existing understanding while publishing the details on website. The customer is responsible for assessing the accuracy of the information at the time of actual purchase.

SynZeal will update these details as per new development or finding in product specification without further noticed.

Nome Químico: (1R,2R)-2-(2-carboxyethyl)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium benzenesulfonate

Sinônimo: Cisatracurium EP Impurity A ; Cisatracurium USP Impurity b ; cis-Quaternary acid

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Sorrisos: COC1=CC2=C(C=C1OC)CC[N@@+](CCC(O)=O)(C)[C@@H]2CC3=CC=C(OC)C(OC)=C3.O=S(C4=CC=CC=C4)([O-])=O

Atracurium cis-Quaternary Acid is chemically (1R,2R)-2-(2-carboxyethyl)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium benzenesulfonate. It is also known as Cisatracurium EP Impurity A ; Cisatracurium USP Impurity b ; cis-Quaternary acid . Atracurium cis-Quaternary Acid is supplied with detailed characterization data compliant with regulatory guideline. Atracurium cis-Quaternary Acid can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Atracurium.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Determination of atracurium, cisatracurium and mivacurium with their impurities in pharmaceutical preparations by liquid chromatography with charged aerosol detection
Agata Błazewicz, Zbigniew Fijałeka,b, Małgorzata Warowna-Grzeskiewicz ,Magdalena Jadach
Journal of Chromatography A, 1217 (2010) 1266–1272
 
Directly Coupled Chiral HPLC-NMR and HPLC-CD Spectroscopy as Complementary Methods for Structural and Enantiomeric Isomer Identification: Application to Atracurium Besylate
Nisha Mistry,Andrew D. Roberts, George E. Tranter,Peter Francis, Ian Barylski, Ismail M. Ismail,§ Jeremy K. Nicholson,| and John C. Lindon
Anal. Chem. 1999, 71, 2838-2843

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