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Chemical Name: Calcium bis[9-[[(2E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1methylpropyl] oxiranyl]methyl]tetrahydro-2H-pyran-2-yl]-3-methylbut-2-enoyl]oxy]nonanoate] dihydrate (as per EP) (αE,2S,3R,4R,5S)-5-[(2S,3S,4S,5S)-2,3-Epoxy-5-hydroxy-4-methylhexyl]tetrahydro-3,4-dihydroxy-β-methyl-2H-pyran-2-crotonic acid, ester with 9-hydroxynonanoic acid, calcium salt (2:1), dihydrate (as per USP)
Synonym: Pseudomonic acid ; Turixin ; trans-Pseudomonic acid
Shipping Temperature: Ambient
HSN Code: 38229010
Country of Origin: India
Smiles: O=C([O-])CCCCCCCCOC(/C=C(C)/C[C@H]1[C@H](O)[C@H](O)[C@@H](CC2O[C@H]2[C@@H](C)[C@@H](O)C)CO1)=O.O=C([O-])CCCCCCCCOC(/C=C(C)/C[C@H]3[C@H](O)[C@H](O)[C@@H](CC4O[C@H]4[C@@H](C)[C@@H](O)C)CO3)=O.[Ca+2]
Mupirocin Calcium Dihydrate is chemically Calcium bis[9-[[(2E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5[[(2S,3S)-3-[(1S,2S)-2-hydroxy-1methylpropyl] oxiranyl]methyl]tetrahydro-2H-pyran-2-yl]-3-methylbut-2-enoyl]oxy]nonanoate] dihydrate (as per EP) (αE,2S,3R,4R,5S)-5-[(2S,3S,4S,5S)-2,3-Epoxy-5-hydroxy-4-methylhexyl]tetrahydro-3,4-dihydroxy-β-methyl-2H-pyran-2-crotonic acid, ester with 9-hydroxynonanoic acid, calcium salt (2:1), dihydrate (as per USP). It is also known as Pseudomonic acid ; Turixin ; trans-Pseudomonic acid. Mupirocin Calcium Dihydrate is supplied with detailed characterization data compliant with regulatory guideline. Mupirocin Calcium Dihydrate can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Mupirocin.
The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.
Analytical method development and validation for simultaneous estimation of halobetasol propionate and mupirocin in the ratio 1:40 by U.V. spectroscopy and RP-HPLC method
By Bana, Arpit; Sathe, Mansi A.; Rajput, Sadhana J.
From International Journal of Pharmaceutical Sciences and Research (2019), 10(3), 1392-1401
Development and validation of analytical method by RP-HPLC technique for determination of mupirocin lithium in pharmaceutical dosage form
By Rele, Rajan V.
From Journal of Chemical and Pharmaceutical Research (2017), 9(10), 249-253