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Chemical Name: 4-((Furan-2-ylmethyl)(nitroso)amino)-2-((furan-2-ylmethyl)amino)-5-sulfamoylbenzoic acid
Shipping Temperature: Ambient
HSN Code: 38229010
Country of Origin: India
Smiles: O=C(O)C1=CC(S(=O)(N)=O)=C(N(N=O)CC2=CC=CO2)C=C1NCC3=CC=CO3
A New Way of Stabilization of Furosemide upon Cryogenic Grinding by Using Acylated Saccharides Matrices. The Role of Hydrogen Bonds in Decomposition MechanismE. Kaminska,*,† K. Adrjanowicz,‡,§ K. Kaminski,§,∥ P. Wlodarczyk,⊥ L. Hawelek,§,⊥ K. Kolodziejczyk,§ M. Tarnacka,§ D. Zakowiecki,# I. Kaczmarczyk-Sedlak,† J. Pilch,∇ and M. PaluchMol. Pharmaceutics 2013, 10, 5, 1824–1835 Effect of Cryogrinding on Chemical Stability of the Sparingly Water-Soluble Drug FurosemideKarolina Adrjanowicz, Kamil Kaminski, Katarzyna Grzybowska, Lukasz Hawelek, Marian Paluch, Irena Gruszka, Daniel Zakowiecki, Wieslaw Sawicki, Przemyslaw Lepek, Wojciech Kamysz & Lukasz GuzikPharmaceutical Research volume 28, pages3220–3236(2011) Implementation of design of experiments for optimization of forced degradation conditions and development of a stability-indicating method for furosemideMoolchandKurmiaSanjayKumaraBhupinderSinghbSaranjitSinghJournal of Pharmaceutical and Biomedical Analysis Volume 96, 5 August 2014, Pages 135-143 Furosemide Determination by First‐Derivative Spectrophotometric MethodIara Lu´cia Tescarollo Dias, Jorge Luiz S. Martins, Graciliano de Oliveira NetoAnalytical Letters, 38: 1159–1166, 2005
N2-Nitroso Furosemide EP Impurity D is chemically 4-((Furan-2-ylmethyl)(nitroso)amino)-2-((furan-2-ylmethyl)amino)-5-sulfamoylbenzoic acid. N2-Nitroso Furosemide EP Impurity D is supplied with detailed characterization data compliant with regulatory guideline. N2-Nitroso Furosemide EP Impurity D can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Furosemide.
The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.