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Picture of Trimetazidine EP Impurity E (3HCl salt)

Trimetazidine EP Impurity E (3HCl salt)

SZ CAT No:SZ-T036018
CAS NoNA
Mol.F.C14H22N2O3 : 3(HCl)
Mol.Wt.266.3 : 3(36.5)
Inv. StatusIn Stock
Rel. CAS No356083-64-2 (free base) ; 2518359-32-3 (dihydrochloride)

Chemical Name: 1-(2,4,5-Trimethoxybenzyl)piperazine Trihydrochloride (as per EP)

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: COC1=C(C=C(OC)C(OC)=C1)CN2CCNCC2.[3HCl]

Stability indicating HPTLC determination of Trimetazidine as bulk drug and in pharmaceutical formulations
Simmy O Thoppil, Rita MCardoza, P.D Amin
Journal of Pharmaceutical and Biomedical Analysis Volume 25, Issue 1, April 2001, Pages 15-20
 
Design of Experiments–Design Space Approach for Development of Chaotropic Chromatography Method for Determination of Trimetazidine Dihydrochloride and Two Impurities
Nenad Milošević, Ana Vemić, Jelena Čolović, Nađa Kostić & Anđelija Malenović
Chromatographia volume 80, pages585–592(2017)
 
Computer—Assisted Optimization and Validation of LC Analysis of Trimetazidine Dihydrochloride and Its Impurities
Mirjana B. Medenica, Darko P. Ivanovic, Igor B. Popovic, Andjelija M. Malenovic, Biljana S. Jancic
Journal of Chromatographic Science, Volume 46, Issue 5, May-June, Pages 430–435
 
Factor Optimization Study to Develop and Validate a Reversed-Phase Thin-Layer Chromatography Method for the Determination of Trimetazidine Dihydrochloride and Its Reported Impurities in Pharmaceuticals
Suzan Mahmoud Soliman
JPC - Journal of Planar Chromatography - Modern TLC Volume/Issue: Volume 32: Issue 4 Page Count: 273–283

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