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Nome Químico: (S)-2-(2-(2-((3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)amino)ethyl)-4,5-dimethoxyphenyl)acetic acid
Shipping Temperature: Ambient
HSN Code: 38229010
Country of Origin: India
Sorrisos: COC1=C(OC)C=C(CCNCCCN(C)C[C@@H]2C(C=C(OC)C(OC)=C3)=C3C2)C(CC(O)=O)=C1
Baixar MSDS
Forced Degradation Studies of Ivabradine and In Silico Toxicology Predictions for Its New Designated ImpuritiesPiotr Pikul,1 Marzena Jamrógiewicz,1,* Joanna Nowakowska,1 Weronika Hewelt-Belka,2,3 and Krzesimir CiuraFront Pharmacol. 2016; 7: 117. Simultaneous determination of chiral and achiral impurities of ivabradine on a cellulose tris(3-chloro-4-methylphenylcarbamate) chiral column using polar organic modeElekFerenczabBélaKovácsabFranciscBodaaMohammadhassanForoughbakhshfasaeicÉva KatalinKelemenbGergőTóthcZoltán-IstvánSzabóJournal of Pharmaceutical and Biomedical Analysis Volume 177, 5 January 2020, 112851 Characterization of degradation products of Ivabradine by LC-HR-MS/MS: a typical case of exhibition of different degradation behaviour in HCl and H2SO4 acid hydrolysisPrinesh N. Patel,a Roshan M. Borkar,b Pradipbhai D. Kalariya,a Rahul P. Gangwal,c Abhay T. Sangamwar,c Gananadhamu Samanthulaa and Srinivas RagampetaJ. Mass Spectrom. 2015, 50, 344–353 Application and Validation of Simple Isocratic HPLC-UV-DAD Method with Dual Wavelength Detection for Ivabradine Determination and Its Application in the Study of Stress DegradationJoanna Nowakowska,1 Piotr Pikul,1,2 Marcin Marszałł,3 and Krzesimir CiuraHindawi Journal of Chemistry Volume 2017, Article ID 2069571, 7 pages Quantitative Determination and Validation of Ivabradine HCL by Stability Indicating RP-HPLC Method and Spectrophotometric Method in Solid Dosage FormShweta Maheshwari 1 , Amit P. Khandhar 2, Anurekha JainEurasian J Anal Chem 2010;5(1):53–62
Ivabradine Open Ring is chemically (S)-2-(2-(2-((3-(((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)amino)ethyl)-4,5-dimethoxyphenyl)acetic acid. Ivabradine Open Ring is supplied with detailed characterization data compliant with regulatory guideline. Ivabradine Open Ring can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ivabradine.
The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.
Ivabradine Hydrochloride
1-Oxo Ivabradine Hydrochloride
N-Demethyl Ivabradine Hydrochloride
Ivabradine Amine Hydrochloride
Ivabradine Impurity 56
Dehydro Ivabradine
Ivabradine chloro Impurity
Ivabradine Iodo Impurity
Ivabradine R-Enantiomer Hydrochloride
Ivabradine Impurity 1
Ivabradine Impurity 2
Ivabradine Impurity 3
Ivabradine Dimer Impurity (HCl salt)
Ivabradine Open Ring
Ivabradine Impurity 6
Ivabradine Impurity 7
Ivabradine Impurity 8
Ivabradine Impurity 9
Hydroxy Ivabradine
Acetyl Ivabradine
Ivabradine Impurity 12
Ivabradine Bisbenzazepine Analog
Ivabradine Impurity 15
Ivabradine Impurity 16
Ivabradine Impurity 17
7-Demethyl Ivabradine (HCl salt)
8-Demethyl Ivabradine (HCl salt)
Ivabradine N-Oxide Impurity
Rac-Ivabradine HCl
Rac-Ivabradine D6
Ivabradine Impurity 20
3-Hydroxy Ivabradine
8-Demethyl Ivabradine
Ivabradine Impurity 23
Ivabradine Impurity 24
7-Demethyl Ivabradine
Ivabradine Impurity 26
5-Hydroxy Ivabradine
Ivabradine Amine
Ivabradine Impurity 29
Ivabradine 12-Isomer Impurity
Ivabradine 12-N Oxide Impurity
Ivabradine Impurity 31
Ivabradine Impurity 33
Ivabradine Impurity 35
Ivabradine Amine Nitroso Impurity
Ivabradine Impurity 37
Ivabradine Impurity 38
Ivabradine Impurity 39
N-Nitroso N-Desmethyl Ivabradine
Ivabradine Impurity 40
Ivabradine Impurity 41
3-Hydroxy Ivabradine Hydrochloride
Ivabradine Impurity 43
Ivabradine Impurity 44
Ivabradine Impurity 45
Ivabradine Impurity 46
Ivabradine Impurity 47
Ivabradine Impurity 13
Ivabradine Impurity 48
Ivabradin Oxalate
Ivabradine Impurity 50
Ivabradine Impurity 51
Ivabradine Impurity 52