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Doxycycline Hydrochloride

Picture of Doxycycline Hydrochloride
SZ CAT No SZ-D049013
CAS No 10592-13-9
Mol.F. C22H24N2O8 : HCl
Mol.Wt. 444.4 : 36.5
Inv. Status Custom Synthesis
Rel. CAS No 564-25-0 (Free base) ; 17086-28-1 (hydrate)


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SynZeal product information given on this website is as per the existing understanding while publishing the details on website. The customer is responsible for assessing the accuracy of the information at the time of actual purchase.

SynZeal will update these details as per new development or finding in product specification without further noticed.

Chemical Name: (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O[C@@](C(O)=C(C1=O)[C@@]2([H])[C@H](C3=CC=CC(O)=C13)C)(C4=O)[C@]([C@H]2O)([H])[C@@H](C(O)=C4C(N)=O)N(C)C.Cl

Doxycycline Hydrochloride is chemically (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride. Doxycycline Hydrochloride is supplied with detailed characterization data compliant with regulatory guideline. Doxycycline Hydrochloride can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Doxycycline.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Rapid liquid chromatographic method for the control of doxycycline and tiamulin residues and their metabolites in vivo assays with pigs: Treatment and depletion
By Cambeiro-Perez, Noelia; Gonzalez-Gomez, Xiana; Rey-Salgueiro, Ledicia; Simal-Gandara, Jesus; Martinez-Carballo, Elena
From Journal of Pharmaceutical and Biomedical Analysis (2020), 190, 113428
 
New HPLC-​MS method for rapid and simultaneous quantification of doxycycline, diethylcarbamazine and albendazole metabolites in rat plasma and organs after concomitant oral administration
By Permana, Andi Dian; Tekko, Ismaiel A.; McCarthy, Helen O.; Donnelly, Ryan F.
From Journal of Pharmaceutical and Biomedical Analysis (2019), 170, 243-253

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