Lopinavir Metabolite M3-M4 (Mixture of Diastereomers)

SZ目录编号:	SZ-L008028
CAS 号	357275-54-8
分子式	C37H48N4O6
分子量	644.8
投资状态	In Stock

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化学名称: (2S)-N-((2S,4S,5S)-5-(2-(2,6-dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-2-(4-hydroxy-2-oxotetrahydropyrimidin-1(2H)-yl)-3-methylbutanamide

异名: Lopinavir 4-Hydroxy Analog

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

微笑: O=C(N[C@H](C[C@H](O)[C@@H](NC(COC(C(C)=CC=C1)=C1C)=O)CC2=CC=CC=C2)CC3=CC=CC=C3)[C@@H](N(CCC(O)N4)C4=O)C(C)C

Stability indicative and cost effective creation and validation of analytical method of Lopinavir and Rilpivirine by high performance liquid chromatography
By Srinivas, L.; Jain, Neelu
From International Journal of Research in Pharmaceutical Sciences (Madurai, India) (2021), 12(1), 786-792

Analytical methods development & validation for simultaneous estimation of lopinavir & ritonavir in pharmaceutical formulation by simultaneous equation method using UV spectrophotometry
By Jadhav, Sarika R.; Alhat, Hemant P.; Joshi, Suhas
From International Research Journal of Pharmacy (2018), 9(8), 57-62

Development and validation of forced degradation studies of lopinavir using RP-HPLC and characterization of degradants by LC-MS/MS
By Bhavyasri, Khagga; Balaram, V. Murali; Nageswarao, R.; Rambabu, D.; Ajitha, M.
From International Journal of Chemical Sciences (2015), 13(1), 551-562

Lopinavir Metabolite M3-M4 (Mixture of Diastereomers) is chemically (2S)-N-((2S,4S,5S)-5-(2-(2,6-dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-2-(4-hydroxy-2-oxotetrahydropyrimidin-1(2H)-yl)-3-methylbutanamide. It is also known as Lopinavir 4-Hydroxy Analog . Lopinavir Metabolite M3-M4 (Mixture of Diastereomers) is supplied with detailed characterization data compliant with regulatory guideline. Lopinavir Metabolite M3-M4 (Mixture of Diastereomers) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lopinavir.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.