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化学名称: (3RS)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid (as per EP)
Shipping Temperature: Ambient
HSN Code: 38229010
Country of Origin: India
微笑: O=C1C2=CC(F)=C(N3CCN(C)CC3)C(OCC4C)=C2N4C=C1C(O)=O
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Use of various β-cyclodextrin derivatives as chiral selectors for the enantiomeric separation of ofloxacin and its five related substances by capillary electrophoresisBolin Zhu , Shuying Xu , Xingjie Guo , Lan Wei , Jia Yu , Tiejie WangJ Sep Sci. 2017 Apr;40(8):1784-1795. Stability Indicating Reversed-Phase High Performance Liquid Chromatography Method for Determination of Impurities in Ofloxacin Tablet FormulationsBobba Venkateswara Reddy,1 Avvaru Praveen Kumar,2 Gosula Venkat Ram Reddy,1 Mohinish Sahai,1 Jadi Sreeramulu,1 and Jung Hag ParkAnalytical Letters, 43: 2653–2662, 2010 Enantioseparation of ofloxacin and its four related substances with ligand exchange–micellar electrokinetic chromatography using copper(II)‐L‐isoleucine complex as chiral selectorYongjing Liu Xiaoying WangChirality Volume29, Issue8 August 2017 Pages 422-429 Multiple Response Optimization of a HPLC Method for the Determination of Enantiomeric Purity of S-OfloxacinValliappan Kannappan & Sai Sandeep MannemalaChromatographia volume 77, pages1203–1211(2014)
Ofloxacin is chemically (3RS)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid (as per EP). Ofloxacin is supplied with detailed characterization data compliant with regulatory guideline. Ofloxacin can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ofloxacin.
The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.
Ofloxacin
Ofloxacin EP Impurity A
Ofloxacin EP Impurity B
Ofloxacin EP Impurity C
Ofloxacin EP Impurity D
Ofloxacin EP Impurity D Ethyl Ester
Ofloxacin EP Impurity E
Ofloxacin EP Impurity F
Ofloxacin Desethylene Impurity
Ofloxacin R-Isomer
(R)-Ofloxacin Carboxylic Acid
Ofloxacin Desfluoro Acid
(R)-Ofloxacin D3
Levofloxacin D3
Ofloxacin D8
Ofloxacin Dihydrooxazole Impurity
Ofloxacin Dimer Impurity