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Sofosbuvir 3',5'-Bis-O-Phosphoramidate alpha-Isomer

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SZ目录编号:	SZ-S010012
CAS 号	NA
分子式	C35H47FN4O12P2
分子量	796.7
投资状态	Custom Synthesis

Product Overview Description Technical Data

化学名称: Isopropyl ((R)-benzyl(((2R,3R,4R,5S)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-(((S)-(((S)-1-isopropoxy-1-oxopropan-2-yl)amino)(phenoxy)phosphoryl)oxy)-4-methyltetrahydrofuran-2-yl)methoxy)phosphoryl)-L-alaninate

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

微笑: F[C@]1(C)[C@H](O[P@](OC2=CC=CC=C2)(N[C@@H](C)C(OC(C)C)=O)=O)[C@@H](CO[P@](CC3=CC=CC=C3)(N[C@H](C(OC(C)C)=O)C)=O)O[C@@H]1N4C(NC(C=C4)=O)=O

Method development and validation for the simultaneous estimation of sofosbuvir and velpatasvir in bulk and tablet dosage forms by RP-HPLC
By Suma, M. S. M.; Gowthami, M.; Latha, P. V. Madhavi; Devi, P. Uma
From Journal of Global Trends in Pharmaceutical Sciences (2021), 12(1), 9037-9043.

Development and validation of RP-HPLC method for the estimation of Sofosbuvir and Ledipasvir in combined dosage form
By Prabhaker, Naik Desai Prabhat; Pankaj, Kapupara
From International Journal of Research in Pharmaceutical Sciences (Madurai, India) (2021), 12(1), 523-529.

Eco-friendly HPTLC method for simultaneous analysis of sofosbuvir and ledipasvir in biological and pharmaceutical samples: Stability indicating study
By El-Yazbi, Amira F.; Elashkar, Nourhan E.; Abdel-Hay, Karim M.; Talaat, Wael; Ahmed, Hytham M.
From Microchemical Journal (2020), 154, 104584.

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SynZeal product information given on this website is as per the existing understanding while publishing the details on website. The customer is responsible for assessing the accuracy of the information at the time of actual purchase.

SynZeal will update these details as per new development or finding in product specification without further noticed.

Sofosbuvir 3',5'-Bis-O-Phosphoramidate alpha-Isomer

SZ目录编号:	SZ-S010012
CAS 号	NA
分子式	C35H47FN4O12P2
分子量	796.7
投资状态	Custom Synthesis

Disclaimer

SynZeal will update these details as per new development or finding in product specification without further noticed.

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

微笑: F[C@]1(C)[C@H](O[P@](OC2=CC=CC=C2)(N[C@@H](C)C(OC(C)C)=O)=O)[C@@H](CO[P@](CC3=CC=CC=C3)(N[C@H](C(OC(C)C)=O)C)=O)O[C@@H]1N4C(NC(C=C4)=O)=O

Sofosbuvir 3',5'-Bis-O-Phosphoramidate alpha-Isomer is chemically Isopropyl ((R)-benzyl(((2R,3R,4R,5S)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-(((S)-(((S)-1-isopropoxy-1-oxopropan-2-yl)amino)(phenoxy)phosphoryl)oxy)-4-methyltetrahydrofuran-2-yl)methoxy)phosphoryl)-L-alaninate. Sofosbuvir 3',5'-Bis-O-Phosphoramidate alpha-Isomer is supplied with detailed characterization data compliant with regulatory guideline. Sofosbuvir 3',5'-Bis-O-Phosphoramidate alpha-Isomer can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Sofosbuvir.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.