9-Desfluoro-11-Dehydroxy-9(11)-Ene Triamcinolone Acetonide

SZ目录编号:	SZ-T028016
CAS 号	5541-37-7
分子式	C24H30O5
分子量	398.5
投资状态	In Stock

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化学名称: (6aS,8aS,8bS,11aR,12aS,12bS)-8b-(2-hydroxyacetyl)-6a,8a,10,10-tetramethyl-1,2,6a,8,8a,8b,11a,12,12a,12b-decahydro-4Hnaphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one

异名: TCA Impurity D

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

微笑: O=C1C=C2CC[C@@]3([H])[C@]4([H])C[C@](OC(C)(C)O5)([H])[C@]5(C(CO)=O)[C@@]4(C)CC=C3[C@@]2(C)C=C1

Δ14-steroidal impurity: preparation, characterization and evaluation, as well development of new HPLC method in drug substance like Triamcinolone Hexacetonide
By Shah, Tejas J.; Thakore, Anant R.; Chheda, Abhay H.; Desai, Geeta R.; Tandel, Harish S.
From Asian Journal of Pharmaceutical Analysis and Medicinal Chemistry (2020), 8(1), 7-15

Resolution and quantitation of triamcinolone acetonide and its coformulated drug in the presence of its impurities and degradation products by HPTLC and HPLC
By Abbas, Samah S.; Hegazy, Maha A.; Hendawy, Hassan A. M.; Weshahy, Soheir A.; Abdelwahab, May H.
From Journal of AOAC International (2018), 101(4), 981-991

Development and validation of a stability-indicating HPLC-UV method for the determination of triamcinolone acetonide and its degradation products in an ointment formulation
By van Heugten, A. J. P.; de Boer, W.; de Vries, W. S.; Markesteijn, C. M. A.; Vromans, H.
From Journal of Pharmaceutical and Biomedical Analysis (2018), 149, 265-270

9-Desfluoro-11-Dehydroxy-9(11)-Ene Triamcinolone Acetonide is chemically (6aS,8aS,8bS,11aR,12aS,12bS)-8b-(2-hydroxyacetyl)-6a,8a,10,10-tetramethyl-1,2,6a,8,8a,8b,11a,12,12a,12b-decahydro-4Hnaphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one. It is also known as TCA Impurity D. 9-Desfluoro-11-Dehydroxy-9(11)-Ene Triamcinolone Acetonide is supplied with detailed characterization data compliant with regulatory guideline. 9-Desfluoro-11-Dehydroxy-9(11)-Ene Triamcinolone Acetonide can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Triamcinolone.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.