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  • Home /
  • Acalabrutinib

Acalabrutinib Related Products

SynZeal is a leading innovator in pharmaceutical reference standards. We supply high-quality Reference Standards of Acalabrutinib, pharmacopeial and non-pharmacopeial Acalabrutinib impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Acalabrutinib impurities reference standards are useful in pharmaceutical research. They are useful in product development, ANDA and DMF filing, quality control (QC), method validation, and stability studies. It is also useful in the identification of unknown impurities and the assessment of genotoxic potential.

Acalabrutinib-related products are thoroughly characterized. Acalabrutinib products are supplied with detailed COA & analytical data meeting regulatory compliance. We can also provide EP/USP traceable standards based on your requirements. The supplied products are re-tested at regular intervals.

Pharmaceutical Reference Standards

Acalabrutinib

Picture of Acalabrutinib
CAT No: SZ-A078001
CAS No: 1420477-60-6
Mol.F. : C26H23N7O2
Mol.Wt. : 465.5
Inv. Status: Custom Synthesis
Rel. CAS No : 2058092-05-8 (Sulfate salt)
SZ-A078001
CAS No:1420477-60-6
Mol.F.: C26H23N7O2
Mol.Wt.: 465.5
Inv. Status: Custom Synthesis
Rel. CAS No : 2058092-05-8 (Sulfate salt)

Acalabrutinib Metabolite M27 (ACP-5862)

Picture of Acalabrutinib Metabolite M27 (ACP-5862)
CAT No: SZ-A078002
CAS No: 2230757-47-6
Mol.F. : C26H23N7O3
Mol.Wt. : 481.5
Inv. Status: Custom Synthesis
SZ-A078002
CAS No:2230757-47-6
Mol.F.: C26H23N7O3
Mol.Wt.: 481.5
Inv. Status: Custom Synthesis

Acalabrutinib Impurity 2

Picture of Acalabrutinib Impurity 2
CAT No: SZ-A078003
CAS No: NA
Mol.F. : C21H19N5O3
Mol.Wt. : 389.4
Inv. Status: Custom Synthesis
SZ-A078003
CAS No:NA
Mol.F.: C21H19N5O3
Mol.Wt.: 389.4
Inv. Status: Custom Synthesis

Acalabrutinib M5 Metabolite

Picture of Acalabrutinib M5 Metabolite
CAT No: SZ-A078004
CAS No: NA
Mol.F. : C36H40N10O8S
Mol.Wt. : 772.8
Inv. Status: Custom Synthesis
SZ-A078004
CAS No:NA
Mol.F.: C36H40N10O8S
Mol.Wt.: 772.8
Inv. Status: Custom Synthesis

Acalabrutinib M10 Metabolite

Picture of Acalabrutinib M10 Metabolite
CAT No: SZ-A078005
CAS No: NA
Mol.F. : C29H30N8O4S
Mol.Wt. : 586.7
Inv. Status: Custom Synthesis
SZ-A078005
CAS No:NA
Mol.F.: C29H30N8O4S
Mol.Wt.: 586.7
Inv. Status: Custom Synthesis

Acalabrutinib Acetaldehyde

Picture of Acalabrutinib Acetaldehyde
CAT No: SZ-A078006
CAS No: NA
Mol.F. : C26H25N7O3
Mol.Wt. : 483.5
Inv. Status: In Stock
SZ-A078006
CAS No:NA
Mol.F.: C26H25N7O3
Mol.Wt.: 483.5
Inv. Status: In Stock

Acalabrutinib M7 Metabolite

Picture of Acalabrutinib M7 Metabolite
CAT No: SZ-A078007
CAS No: NA
Mol.F. : C31H33N9O5S
Mol.Wt. : 643.7
Inv. Status: Custom Synthesis
SZ-A078007
CAS No:NA
Mol.F.: C31H33N9O5S
Mol.Wt.: 643.7
Inv. Status: Custom Synthesis

(5-Chloropyrazin-2-yl)methanamine

Picture of (5-Chloropyrazin-2-yl)methanamine
CAT No: SZ-A078008
CAS No: 1060814-53-0
Mol.F. : C5H6ClN3
Mol.Wt. : 143.6
Inv. Status: Custom Synthesis
Rel. CAS No : 1794737-26-0 (HCl salt)
SZ-A078008
CAS No:1060814-53-0
Mol.F.: C5H6ClN3
Mol.Wt.: 143.6
Inv. Status: Custom Synthesis
Rel. CAS No : 1794737-26-0 (HCl salt)

(3,5-Dichloropyrazin-2-yl)methanamine

Picture of (3,5-Dichloropyrazin-2-yl)methanamine
CAT No: SZ-A078009
CAS No: 1211531-66-6
Mol.F. : C5H5Cl2N3
Mol.Wt. : 178.0
Inv. Status: Out of Stock
Rel. CAS No : 2089319-25-3 (HCl salt)
SZ-A078009
CAS No:1211531-66-6
Mol.F.: C5H5Cl2N3
Mol.Wt.: 178.0
Inv. Status: Out of Stock
Rel. CAS No : 2089319-25-3 (HCl salt)

Acalabrutinib Impurity 7

Picture of Acalabrutinib Impurity 7
CAT No: SZ-A078010
CAS No: 2180911-32-2
Mol.F. : C18H21BN2O3
Mol.Wt. : 324.2
Inv. Status: Custom Synthesis
SZ-A078010
CAS No:2180911-32-2
Mol.F.: C18H21BN2O3
Mol.Wt.: 324.2
Inv. Status: Custom Synthesis

Acalabrutinib Impurity 8

Picture of Acalabrutinib Impurity 8
CAT No: SZ-A078011
CAS No: 2180911-29-7
Mol.F. : C18H21BN2O3
Mol.Wt. : 324.2
Inv. Status: Custom Synthesis
SZ-A078011
CAS No:2180911-29-7
Mol.F.: C18H21BN2O3
Mol.Wt.: 324.2
Inv. Status: Custom Synthesis

Propiolic Acid

Picture of Propiolic Acid
CAT No: SZ-A078012
CAS No: 471-25-0
Mol.F. : C3H2O2
Mol.Wt. : 70.0
Inv. Status: Custom Synthesis
Rel. CAS No : 920-38-7 (Na salt) ; 1968-46-3 (K salt)
SZ-A078012
CAS No:471-25-0
Mol.F.: C3H2O2
Mol.Wt.: 70.0
Inv. Status: Custom Synthesis
Rel. CAS No : 920-38-7 (Na salt) ; 1968-46-3 (K salt)

Acalabrutinib Impurity 9

Picture of Acalabrutinib Impurity 9
CAT No: SZ-A078013
CAS No: NA
Mol.F. : C18H18BrN5O2
Mol.Wt. : 416.3
Inv. Status: Custom Synthesis
SZ-A078013
CAS No:NA
Mol.F.: C18H18BrN5O2
Mol.Wt.: 416.3
Inv. Status: Custom Synthesis

Acalabrutinib Impurity 10

Picture of Acalabrutinib Impurity 10
CAT No: SZ-A078014
CAS No: NA
Mol.F. : C18H18BrN5O2
Mol.Wt. : 416.3
Inv. Status: Custom Synthesis
SZ-A078014
CAS No:NA
Mol.F.: C18H18BrN5O2
Mol.Wt.: 416.3
Inv. Status: Custom Synthesis

Acalabrutinib Impurity 11

Picture of Acalabrutinib Impurity 11
CAT No: SZ-A078015
CAS No: 2490433-97-9
Mol.F. : C30H25N7O3
Mol.Wt. : 531.6
Inv. Status: In Stock
SZ-A078015
CAS No:2490433-97-9
Mol.F.: C30H25N7O3
Mol.Wt.: 531.6
Inv. Status: In Stock

Acalabrutinib Impurity 12

Picture of Acalabrutinib Impurity 12
CAT No: SZ-A078016
CAS No: NA
Mol.F. : C26H23N7O3
Mol.Wt. : 481.5
Inv. Status: Custom Synthesis
SZ-A078016
CAS No:NA
Mol.F.: C26H23N7O3
Mol.Wt.: 481.5
Inv. Status: Custom Synthesis

Acalabrutinib Impurity 13

Picture of Acalabrutinib Impurity 13
CAT No: SZ-A078017
CAS No: NA
Mol.F. : C26H23N7O3
Mol.Wt. : 481.5
Inv. Status: Custom Synthesis
SZ-A078017
CAS No:NA
Mol.F.: C26H23N7O3
Mol.Wt.: 481.5
Inv. Status: Custom Synthesis

Acalabrutinib Impurity 14

Picture of Acalabrutinib Impurity 14
CAT No: SZ-A078018
CAS No: NA
Mol.F. : C47H42N12O3
Mol.Wt. : 822.9
Inv. Status: Custom Synthesis
SZ-A078018
CAS No:NA
Mol.F.: C47H42N12O3
Mol.Wt.: 822.9
Inv. Status: Custom Synthesis

(5-Chloropyrazin-2-yl)methanamine Hydrochloride

Picture of (5-Chloropyrazin-2-yl)methanamine Hydrochloride
CAT No: SZ-A078020
CAS No: 1794737-26-0
Mol.F. : C5H6ClN3 : HCl
Mol.Wt. : 143.6 : 36.5
Inv. Status: Custom Synthesis
Rel. CAS No : 1060814-53-0 (free base)
SZ-A078020
CAS No:1794737-26-0
Mol.F.: C5H6ClN3 : HCl
Mol.Wt.: 143.6 : 36.5
Inv. Status: Custom Synthesis
Rel. CAS No : 1060814-53-0 (free base)

(3,5-Dichloropyrazin-2-yl)methanamine Hydrochloride

Picture of (3,5-Dichloropyrazin-2-yl)methanamine Hydrochloride
CAT No: SZ-A078021
CAS No: 2089319-25-3
Mol.F. : C5H5Cl2N3 : HCl
Mol.Wt. : 178.0 : 36.5
Inv. Status: Custom Synthesis
Rel. CAS No : 1211531-66-6 (free base)
SZ-A078021
CAS No:2089319-25-3
Mol.F.: C5H5Cl2N3 : HCl
Mol.Wt.: 178.0 : 36.5
Inv. Status: Custom Synthesis
Rel. CAS No : 1211531-66-6 (free base)

Acalabrutinib Dimer Impurity

Picture of Acalabrutinib Dimer Impurity
CAT No: SZ-A078024
CAS No: NA
Mol.F. : C52H46N14O4
Mol.Wt. : 931.0
Inv. Status: Custom Synthesis
SZ-A078024
CAS No:NA
Mol.F.: C52H46N14O4
Mol.Wt.: 931.0
Inv. Status: Custom Synthesis

Acalabrutinib Impurity 15

Picture of Acalabrutinib Impurity 15
CAT No: SZ-A078025
CAS No: NA
Mol.F. : C18H21BN2O3
Mol.Wt. : 324.2
Inv. Status: Custom Synthesis
SZ-A078025
CAS No:NA
Mol.F.: C18H21BN2O3
Mol.Wt.: 324.2
Inv. Status: Custom Synthesis

Acalabrutinib Impurity 16

Picture of Acalabrutinib Impurity 16
CAT No: SZ-A078026
CAS No: 864759-38-6
Mol.F. : C18H21BN2O3
Mol.Wt. : 324.2
Inv. Status: Custom Synthesis
SZ-A078026
CAS No:864759-38-6
Mol.F.: C18H21BN2O3
Mol.Wt.: 324.2
Inv. Status: Custom Synthesis

Acalabrutinib Impurity 17

Picture of Acalabrutinib Impurity 17
CAT No: SZ-A078027
CAS No: 2412166-56-2
Mol.F. : C30H25N7O3
Mol.Wt. : 531.6
Inv. Status: In Stock
SZ-A078027
CAS No:2412166-56-2
Mol.F.: C30H25N7O3
Mol.Wt.: 531.6
Inv. Status: In Stock

Acalabrutinib Impurity 18

Picture of Acalabrutinib Impurity 18
CAT No: SZ-A078028
CAS No: 1148-11-4
Mol.F. : C13H15NO4
Mol.Wt. : 249.3
Inv. Status: Custom Synthesis
Rel. CAS No : 264197-10-6 (sodium salt)
SZ-A078028
CAS No:1148-11-4
Mol.F.: C13H15NO4
Mol.Wt.: 249.3
Inv. Status: Custom Synthesis
Rel. CAS No : 264197-10-6 (sodium salt)

Acalabrutinib Impurity 19

Picture of Acalabrutinib Impurity 19
CAT No: SZ-A078029
CAS No: 939412-86-9
Mol.F. : C5H6ClN3 : HCl
Mol.Wt. : 143.6 : 36.5
Inv. Status: Custom Synthesis
Rel. CAS No : 771581-15-8 (free base)
SZ-A078029
CAS No:939412-86-9
Mol.F.: C5H6ClN3 : HCl
Mol.Wt.: 143.6 : 36.5
Inv. Status: Custom Synthesis
Rel. CAS No : 771581-15-8 (free base)

Acalabrutinib Impurity 20

Picture of Acalabrutinib Impurity 20
CAT No: SZ-A078030
CAS No: 1418307-17-1
Mol.F. : C18H19ClN4O3
Mol.Wt. : 374.8
Inv. Status: Custom Synthesis
SZ-A078030
CAS No:1418307-17-1
Mol.F.: C18H19ClN4O3
Mol.Wt.: 374.8
Inv. Status: Custom Synthesis

Acalabrutinib Impurity 21

Picture of Acalabrutinib Impurity 21
CAT No: SZ-A078031
CAS No: 1418307-18-2
Mol.F. : C18H17ClN4O2
Mol.Wt. : 356.8
Inv. Status: Custom Synthesis
SZ-A078031
CAS No:1418307-18-2
Mol.F.: C18H17ClN4O2
Mol.Wt.: 356.8
Inv. Status: Custom Synthesis

Acalabrutinib Impurity 22

Picture of Acalabrutinib Impurity 22
CAT No: SZ-A078032
CAS No: 1420478-87-0
Mol.F. : C18H16BrClN4O2
Mol.Wt. : 435.7
Inv. Status: Custom Synthesis
SZ-A078032
CAS No:1420478-87-0
Mol.F.: C18H16BrClN4O2
Mol.Wt.: 435.7
Inv. Status: Custom Synthesis

Acalabrutinib Impurity 23

Picture of Acalabrutinib Impurity 23
CAT No: SZ-A078033
CAS No: NA
Mol.F. : C18H17BrN4O3
Mol.Wt. : 417.3
Inv. Status: Custom Synthesis
SZ-A078033
CAS No:NA
Mol.F.: C18H17BrN4O3
Mol.Wt.: 417.3
Inv. Status: Custom Synthesis

Acalabrutinib Impurity 24

Picture of Acalabrutinib Impurity 24
CAT No: SZ-A078034
CAS No: 2198380-46-8
Mol.F. : C18H18BrN5O2
Mol.Wt. : 416.3
Inv. Status: Custom Synthesis
SZ-A078034
CAS No:2198380-46-8
Mol.F.: C18H18BrN5O2
Mol.Wt.: 416.3
Inv. Status: Custom Synthesis

Acalabrutinib M2 Metabolite

Picture of Acalabrutinib M2 Metabolite
CAT No: SZ-A078035
CAS No: NA
Mol.F. : C21H19N5O4
Mol.Wt. : 405.4
Inv. Status: Custom Synthesis
SZ-A078035
CAS No:NA
Mol.F.: C21H19N5O4
Mol.Wt.: 405.4
Inv. Status: Custom Synthesis

Acalabrutinib M3 Metabolite

Picture of Acalabrutinib M3 Metabolite
CAT No: SZ-A078036
CAS No: NA
Mol.F. : C22H18N6O4
Mol.Wt. : 430.4
Inv. Status: Custom Synthesis
SZ-A078036
CAS No:NA
Mol.F.: C22H18N6O4
Mol.Wt.: 430.4
Inv. Status: Custom Synthesis

Acalabrutinib M16 Metabolite

Picture of Acalabrutinib M16 Metabolite
CAT No: SZ-A078037
CAS No: NA
Mol.F. : C26H25N7O3
Mol.Wt. : 483.5
Inv. Status: Custom Synthesis
SZ-A078037
CAS No:NA
Mol.F.: C26H25N7O3
Mol.Wt.: 483.5
Inv. Status: Custom Synthesis

Acalabrutinib M24 Metabolite

Picture of Acalabrutinib M24 Metabolite
CAT No: SZ-A078038
CAS No: NA
Mol.F. : C26H27N7O2
Mol.Wt. : 469.5
Inv. Status: Custom Synthesis
SZ-A078038
CAS No:NA
Mol.F.: C26H27N7O2
Mol.Wt.: 469.5
Inv. Status: Custom Synthesis

Acalabrutinib M45 Metabolite

Picture of Acalabrutinib M45 Metabolite
CAT No: SZ-A078039
CAS No: NA
Mol.F. : C26H27N7O3
Mol.Wt. : 485.5
Inv. Status: Custom Synthesis
SZ-A078039
CAS No:NA
Mol.F.: C26H27N7O3
Mol.Wt.: 485.5
Inv. Status: Custom Synthesis

Acalabrutinib M25 Metabolite

Picture of Acalabrutinib M25 Metabolite
CAT No: SZ-A078040
CAS No: NA
Mol.F. : C26H21N7O2
Mol.Wt. : 463.5
Inv. Status: Custom Synthesis
SZ-A078040
CAS No:NA
Mol.F.: C26H21N7O2
Mol.Wt.: 463.5
Inv. Status: Custom Synthesis

Acalabrutinib M14 Metabolite

Picture of Acalabrutinib M14 Metabolite
CAT No: SZ-A078041
CAS No: NA
Mol.F. : C26H23N7O3
Mol.Wt. : 481.5
Inv. Status: Custom Synthesis
SZ-A078041
CAS No:NA
Mol.F.: C26H23N7O3
Mol.Wt.: 481.5
Inv. Status: Custom Synthesis

Acalabrutinib R-Isomer

Picture of Acalabrutinib R-Isomer
CAT No: SZ-A078042
CAS No: 1952316-43-6
Mol.F. : C26H23N7O2
Mol.Wt. : 465.5
Inv. Status: Under Synthesis
SZ-A078042
CAS No:1952316-43-6
Mol.F.: C26H23N7O2
Mol.Wt.: 465.5
Inv. Status: Under Synthesis

Acalabrutinib 8-Hydroxy Impurity

Picture of Acalabrutinib 8-Hydroxy Impurity
CAT No: SZ-A078043
CAS No: NA
Mol.F. : C26H22N6O3
Mol.Wt. : 466.5
Inv. Status: In Stock
SZ-A078043
CAS No:NA
Mol.F.: C26H22N6O3
Mol.Wt.: 466.5
Inv. Status: In Stock

Acalabrutinib Acetyl Impurity

Picture of Acalabrutinib Acetyl Impurity
CAT No: SZ-A078044
CAS No: NA
Mol.F. : C24H23N7O2
Mol.Wt. : 441.5
Inv. Status: Custom Synthesis
SZ-A078044
CAS No:NA
Mol.F.: C24H23N7O2
Mol.Wt.: 441.5
Inv. Status: Custom Synthesis

Acalabrutinib Dihydrate

Picture of Acalabrutinib Dihydrate
CAT No: SZ-A078045
CAS No: 2648852-74-6
Mol.F. : C26H23N7O2 : 2(H2O)
Mol.Wt. : 465.5 : 2(18.0)
Inv. Status: In Stock
Rel. CAS No : 1420477-60-6 (free base) ; 2058092-05-8 (sulfate salt)
SZ-A078045
CAS No:2648852-74-6
Mol.F.: C26H23N7O2 : 2(H2O)
Mol.Wt.: 465.5 : 2(18.0)
Inv. Status: In Stock
Rel. CAS No : 1420477-60-6 (free base) ; 2058092-05-8 (sulfate salt)

Acalabrutinib Impurity 25

Picture of Acalabrutinib Impurity 25
CAT No: SZ-A078046
CAS No: 1420478-90-5
Mol.F. : C22H21N7O
Mol.Wt. : 399.5
Inv. Status: In Stock
Rel. CAS No : 2241641-09-6 (trihydrochloride) ; 2413368-02-0 (oxalate salt)
SZ-A078046
CAS No:1420478-90-5
Mol.F.: C22H21N7O
Mol.Wt.: 399.5
Inv. Status: In Stock
Rel. CAS No : 2241641-09-6 (trihydrochloride) ; 2413368-02-0 (oxalate salt)

Acalabrutinib Benzyl Impurity

Picture of Acalabrutinib Benzyl Impurity
CAT No: SZ-A078048
CAS No: NA
Mol.F. : C29H27N7O
Mol.Wt. : 489.6
Inv. Status: Custom Synthesis
SZ-A078048
CAS No:NA
Mol.F.: C29H27N7O
Mol.Wt.: 489.6
Inv. Status: Custom Synthesis

Acalabrutinib Impurity 26

Picture of Acalabrutinib Impurity 26
CAT No: SZ-A078049
CAS No: 6404-31-5
Mol.F. : C13H15NO4
Mol.Wt. : 249.3
Inv. Status: Custom Synthesis
SZ-A078049
CAS No:6404-31-5
Mol.F.: C13H15NO4
Mol.Wt.: 249.3
Inv. Status: Custom Synthesis

Stable Isotopes and Metabolites

Acalabrutinib D4

Picture of Acalabrutinib D4
CAT No: SZ-A078D01
CAS No: NA
Mol.F. : C26H19D4N7O2
Mol.Wt. : 469.5
Inv. Status: Custom Synthesis
SZ-A078D01
CAS No:NA
Mol.F.: C26H19D4N7O2
Mol.Wt.: 469.5
Inv. Status: Custom Synthesis

Acalabrutinib Metabolite M27 (ACP-5862)-D4

Picture of Acalabrutinib Metabolite M27 (ACP-5862)-D4
CAT No: SZ-A078D02
CAS No: NA
Mol.F. : C26H19D4N7O3
Mol.Wt. : 485.5
Inv. Status: Custom Synthesis
SZ-A078D02
CAS No:NA
Mol.F.: C26H19D4N7O3
Mol.Wt.: 485.5
Inv. Status: Custom Synthesis

Acalabrutinib D3

Picture of Acalabrutinib D3
CAT No: SZ-A078D03
CAS No: NA
Mol.F. : C26H20D3N7O2
Mol.Wt. : 468.5
Inv. Status: Custom Synthesis
SZ-A078D03
CAS No:NA
Mol.F.: C26H20D3N7O2
Mol.Wt.: 468.5
Inv. Status: Custom Synthesis

Possible Nitroso Standards

Acalabrutinib Nitroso Impurity 1

Picture of Acalabrutinib Nitroso Impurity 1
CAT No: SZ-A078047
CAS No: NA
Mol.F. : C22H20N8O2
Mol.Wt. : 428.5
Inv. Status: Custom Synthesis
SZ-A078047
CAS No:NA
Mol.F.: C22H20N8O2
Mol.Wt.: 428.5
Inv. Status: Custom Synthesis

Acalabrutinib Nitroso Impurity 2

Picture of Acalabrutinib Nitroso Impurity 2
CAT No: SZ-A078050
CAS No: NA
Mol.F. : C17H16N6O3
Mol.Wt. : 352.4
Inv. Status: Custom Synthesis
SZ-A078050
CAS No:NA
Mol.F.: C17H16N6O3
Mol.Wt.: 352.4
Inv. Status: Custom Synthesis