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Acebrophylline

Picture of Acebrophylline
SZ CAT No SZ-A096001
CAS No 96989-76-3
Mol.F. C13H18Br2N2O : C9H10N4O4
Mol.Wt. 378.1 : 238.2
Inv. Status In Stock
Rel. CAS No 18683-91-5 (Free base)


Disclaimer

SynZeal product information given on this website is as per the existing understanding while publishing the details on website. The customer is responsible for assessing the accuracy of the information at the time of actual purchase.

SynZeal will update these details as per new development or finding in product specification without further noticed.

Chemical Name: (1R,4R)-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexan-1-ol 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)acetate

Synonym: Ambromucil ; Broncomnes ; Surfolase

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: NC1=C(C=C(Br)C=C1Br)CN[C@H]2CC[C@H](O)CC2.OC(CN3C(C(N(C)C4=O)=O)=C(N4C)N=C3)=O

Acebrophylline is chemically (1R,4R)-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexan-1-ol 2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)acetate. It is also known as Ambromucil ; Broncomnes ; Surfolase. Acebrophylline is supplied with detailed characterization data compliant with regulatory guideline. Acebrophylline can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Acebrophylline.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

A New Stability Indicating RP-​HPLC method for simultaneous estimation of acebrophylline and N-​acetylcysteine in tablet dosage form and its validation as per ICH guidelines
By Kathirvel, S.; Indukala, P. C.; Sruthi, Mohan; Gayathri, Ramya M.; Rajesh, A.
From International Journal of Pharmacy and Pharmaceutical Research (2019), 16(2), 422-435
 
Development and validation of stability-​indicating high-​performance thin-​layer chromatography method for the determination of acebrophylline and doxofylline in bulk and combined dosage form
By Sakhare, Ram S.; Pekamwar, Sanjay S.
From Journal of Pharmacy Research (Mohali, India) (2018), 12(3), 339-345
 
Development and validation of derivative spectroscopic method for estimation of acebrophylline in bulk and its dosage form & in presence of impurity, ambroxol HCl
By Solanki, Bhagavati; Trivedi, Harshal; Khodiyar, Ankita; Tandel, Falguni; Jha, Lalit Lata; Rajesh, K. S.
From Pharmagene (2013), 1(1), 7-11
 

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