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Cefazolin EP Impurity B

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SZ CAT No:	SZ-C016003
CAS No	2384108-14-7
Mol.F.	C16H20N4O4S3
Mol.Wt.	428.5
Inv. Status	In Stock

Product Overview Description Technical Data

Chemical Name: (6R,7R)-7-[(2,2-Dimethylpropanoyl)amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (as per EP); (6R,7R)-3-((5-Methyl-1,3,4-thiadiazol-2-ylthio)methyl)-8-oxo-7-pivalamido-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (as per USP)

Synonym: Cefazolin Pivaloyl (USP)

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C(C(N12)=C(CSC3=NN=C(C)S3)CS[C@]2([H])[C@H](NC(C(C)(C)C)=O)C1=O)O

Embryo and developmental toxicity of cefazolin sodium impurities in zebrafish
By Chen, Bo; Gao, Zhu-Qing; Liu, Ying; Zheng, Yang-Min; Han, Ying; Zhang, Jing-Pu; Hu, chang-Qin
From Frontiers in Pharmacology (2017), 8, 403/1-403/13

Stability of cefazolin sodium for injection in different solvents
By Peng, Yan; Zhang, Ling-li; Shen, Bing-zheng; Wu, Yue; Zhou, Ding-shan; Song, Jin-chun
From Xiandai Yaowu Yu Linchuang (2014), 29(7), 813-817

Comparison study of impurity contents of cefazolin sodium pentahydrate and cefazolin sodium
By Chen, Yong-gang; Ma, Chuan-xue; Yang, Qing; Liu, Xiao-ling; Li, Fan; Lu, Xiang; Sun, Yuan-feng
From Zhongguo Yaofang (2013), 24(25), 2383-2386

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SynZeal will update these details as per new development or finding in product specification without further noticed.

Cefazolin EP Impurity B

SZ CAT No:	SZ-C016003
CAS No	2384108-14-7
Mol.F.	C16H20N4O4S3
Mol.Wt.	428.5
Inv. Status	In Stock

Disclaimer

SynZeal will update these details as per new development or finding in product specification without further noticed.

Synonym: Cefazolin Pivaloyl (USP)

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C(C(N12)=C(CSC3=NN=C(C)S3)CS[C@]2([H])[C@H](NC(C(C)(C)C)=O)C1=O)O

Cefazolin EP Impurity B is chemically (6R,7R)-7-[(2,2-Dimethylpropanoyl)amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (as per EP); (6R,7R)-3-((5-Methyl-1,3,4-thiadiazol-2-ylthio)methyl)-8-oxo-7-pivalamido-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (as per USP). It is also known as Cefazolin Pivaloyl (USP). Cefazolin EP Impurity B is supplied with detailed characterization data compliant with regulatory guideline. Cefazolin EP Impurity B can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cefazolin.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.