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Chemical Name: (2E,4E,6E,8E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid (as per EP); (all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid (as per USP)
Synonym: Acitretinoin ; Etretin ; Neotigason ; Soriatane ; TMMP ; all-trans-Acitretin
Shipping Temperature: Ambient
HSN Code: 38229010
Country of Origin: India
Smiles: COC1=C(C)C(C)=C(/C=C/C(C)=C/C=C/C(C)=C/C(O)=O)C(C)=C1
Acitretin is chemically (2E,4E,6E,8E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid (as per EP); (all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid (as per USP). It is also known as Acitretinoin ; Etretin ; Neotigason ; Soriatane ; TMMP ; all-trans-Acitretin. Acitretin is supplied with detailed characterization data compliant with regulatory guideline. Acitretin can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Acitretin.
The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.
A novel validated stability indicating RP RP-HPLC method for determination of Acitretin in bulk and pharmaceutical formulation
By Priyadarshini, G. Indira; Suneetha, A.; Mounika, V.; Sirisha, Y.
From International Research Journal of Pharmacy (2017), 8(4), 92-94
Separation of all-trans- and 13-cis-isomers of acitretin on a reversed-phase column, optimization of stability conditions and their simultaneous quantitation in human plasma by liquid chromatography-tandem mass spectrometry
By Sharma, Primal; Soni, Kanchan; Guttikar, Swati; Singhal, Puran; Patel, Daxesh P.; Shrivastav, Pranav S.
From Analytical Methods (2012), 4(3), 791-806