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Desfluoro Nebivolol (SSRR and RRSS)

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SZ CAT No:	SZ-N020074
CAS No	NA
Mol.F.	C22H26FNO4
Mol.Wt.	387.5
Inv. Status	In Stock

Product Overview Description Technical Data

Chemical Name: (R)-1-((R)-Chroman-2-yl)-2-(((S)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethan-1-ol compound with (S)-1-((S)-chroman-2-yl)-2-(((R)-2-((R)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethan-1-ol (1:1)

Synonym: Desfluoro Nebivolol (Mixture of Diastereomers)

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O[C@@H]([C@H]1CCC2=C(O1)C=CC=C2)CNC[C@@H]([C@@H]3CCC4=C(O3)C=CC(F)=C4)O.O[C@H]([C@@H]5CCC6=C(O5)C=CC=C6)CNC[C@H]([C@H]7CCC8=C(O7)C=CC(F)=C8)O

Development and validation of a stability-indicating reverse phase ultra performance liquid chromatographic method for the estimation of nebivolol impurities in active pharmaceutical ingredients and pharmaceutical formulation
Veera Raghava Raju Thummala, Mohana Krishna Lanka
Se Pu. 2015 Oct;33(10):1051-8.

Stability-Indicating RP-UPLC Method Development and Validation for the Process Related Impurities of Nebivolol and Structural Characterization of Its Forced Degradation Products by LC-MS/MS
Prasad Kancherla1* , Pallavi Alegete1 , Srinivas Keesari2 , Bhavyasri Khagga1 , Sridhar Siddiraju3 , Mukkanti Khagga1 and Parthasarathi Das
British Journal of Pharmaceutical Research 14(6): 1-13, 2016

Liquid chromatographic impurity profiling of Nebivolol Hydrochloride from bulk drug
Sachin Uttamrao Kokil*1 , Manish Sudesh Bhatia
Scholars Research Library Der Pharma Chemica, 2009, 1(2): 177-187

A Sensitive and Selective GC-MS Analysis of Process Related Genotoxic Impurities of Nebivolol Hydrochloride
Vijaya Lakshmi Maddala, K. Venugopal, P.C. Ray, K.M.V.N. Rao

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SynZeal product information given on this website is as per the existing understanding while publishing the details on website. The customer is responsible for assessing the accuracy of the information at the time of actual purchase.

SynZeal will update these details as per new development or finding in product specification without further noticed.

Desfluoro Nebivolol (SSRR and RRSS)

SZ CAT No:	SZ-N020074
CAS No	NA
Mol.F.	C22H26FNO4
Mol.Wt.	387.5
Inv. Status	In Stock

Disclaimer

SynZeal will update these details as per new development or finding in product specification without further noticed.

Synonym: Desfluoro Nebivolol (Mixture of Diastereomers)

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O[C@@H]([C@H]1CCC2=C(O1)C=CC=C2)CNC[C@@H]([C@@H]3CCC4=C(O3)C=CC(F)=C4)O.O[C@H]([C@@H]5CCC6=C(O5)C=CC=C6)CNC[C@H]([C@H]7CCC8=C(O7)C=CC(F)=C8)O

Desfluoro Nebivolol (SSRR and RRSS) is chemically (R)-1-((R)-Chroman-2-yl)-2-(((S)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethan-1-ol compound with (S)-1-((S)-chroman-2-yl)-2-(((R)-2-((R)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethan-1-ol (1:1). It is also known as Desfluoro Nebivolol (Mixture of Diastereomers). Desfluoro Nebivolol (SSRR and RRSS) is supplied with detailed characterization data compliant with regulatory guideline. Desfluoro Nebivolol (SSRR and RRSS) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nebivolol.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.