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Doxazosin D8

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SZ CAT No:	SZ-D007D01
CAS No	1126848-44-9
Mol.F.	C23H17D8N5O5
Mol.Wt.	459.5
Inv. Status	Custom Synthesis

Product Overview Description Technical Data

Chemical Name: (4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl-2,2,3,3,5,5,6,6-d8)(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanone

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: NC1=NC(N2C([2H])([2H])C([2H])([2H])N(C(C3OC4=CC=CC=C4OC3)=O)C([2H])([2H])C2([2H])[2H])=NC5=C1C=C(OC)C(OC)=C5

Thermal analysis study of antihypertensive drug doxazosin mesilate
Ali K.AttiaMona M.Abdel-MoetySamar G.Abdel-Hamid
Arabian Journal of Chemistry Volume 10, Supplement 1, February 2017, Pages S334-S338

Separation, Characterization, and Quantitation of Process-Related Substances of the Anti-Hypertensive Drug Doxazosin Mesylate by Reversed-Phase LC with PDA and ESI-MS as Detectors
R. Nageswara Rao1,*, D. Nagaraju1, A.K. Das2, and Nivedita Jena
J Chromatogr Sci. 2007 Feb;45(2):63-9.

Validation and pharmacokinetic application of a method for determination of doxazosin in human plasma by high-performance liquid chromatography
Pattana Sripalakit,1,2* Penporn Nermhom2 and Aurasorn Saraphanchotiwitthaya3
Biomedical chromatography biomed. chromatogr. 20: 729–735 (2006)

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SynZeal will update these details as per new development or finding in product specification without further noticed.

Doxazosin D8

SZ CAT No:	SZ-D007D01
CAS No	1126848-44-9
Mol.F.	C23H17D8N5O5
Mol.Wt.	459.5
Inv. Status	Custom Synthesis

Disclaimer

SynZeal will update these details as per new development or finding in product specification without further noticed.

Chemical Name: (4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl-2,2,3,3,5,5,6,6-d8)(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanone

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: NC1=NC(N2C([2H])([2H])C([2H])([2H])N(C(C3OC4=CC=CC=C4OC3)=O)C([2H])([2H])C2([2H])[2H])=NC5=C1C=C(OC)C(OC)=C5

Doxazosin D8 is chemically (4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl-2,2,3,3,5,5,6,6-d8)(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanone. Doxazosin D8 is supplied with detailed characterization data compliant with regulatory guideline. Doxazosin D8 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Doxazosin.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.