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Finasteride Dihydro Carboxylic Acid Methyl Ester

Picture of Finasteride Dihydro Carboxylic Acid Methyl Ester
SZ CAT No SZ-F013009
CAS No 73671-92-8
Mol.F. C20H31NO3
Mol.Wt. 333.5
Inv. Status In Stock


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Chemical Name: (5α,17β)-3-Oxo-4-aza-androstane-17-carboxylic acid methyl ester ;

Synonym: Finasteride Dihydro Carboxylic Acid Methyl Ester ; 1,2-Dihydro Finasteride Carboxylic Acid Methyl Ester ;

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: C[C@@]12[C@@H](C(OC)=O)CC[C@@]1([H])[C@]3([H])CC[C@@]4([H])NC(CC[C@]4(C)[C@@]3([H])CC2)=O

Finasteride Dihydro Carboxylic Acid Methyl Ester is chemically (5α,17β)-3-Oxo-4-aza-androstane-17-carboxylic acid methyl ester ;. It is also known as Finasteride Dihydro Carboxylic Acid Methyl Ester ; 1,2-Dihydro Finasteride Carboxylic Acid Methyl Ester ;. Finasteride Dihydro Carboxylic Acid Methyl Ester is supplied with detailed characterization data compliant with regulatory guideline. Finasteride Dihydro Carboxylic Acid Methyl Ester can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Finasteride.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Mechanism-Based Inhibition of Human Steroid 5R-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADP-Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor
Herbert G. Bull,* Margarita Garcia-Calvo, Stefan Andersson,† Walter F. Baginsky, H. Karen Chan,‡ Dina E. Ellsworth,§ Randall R. Miller, Ralph A. Stearns, Raman K. Bakshi, Gary H. Rasmusson, Richard L. Tolman, Robert W. Myers, John W. Kozarich, and Georgianna S. Harris
J. Am. Chem. Soc. 1996, 118, 2359-2365
 
A systematic study of determination and validation of finasteride impurities using liquid chromatography
Aysen KurtCucuaSerapSakaryabHulya DemircanDemiraSarfrazAhmad
Arabian Journal of Chemistry Volume 13, Issue 2, February 2020, Pages 3783-3789
 
A Stability Indicating UPLC Method for Finasteride and Its Related Impurities
Y. Koti Reddy1,3, G. V. Subba Reddy2, K. N. Jaya Veera3, Kishore Kumar Hotha
American Journal of Analytical Chemistry Vol.3 No.11(2012), Article ID:24469,9 pages
 
Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids: A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations
B. K. Matuszewski,* M. L. Constanzer, and C. M. Chavez-Eng
Anal. Chem. 1998, 70, 882-889
 
High-performance liquid chromatographic determination of finasteride in human plasma using direct injection with column switching
Terukazu Takano*, Shunsuke Hata
Journal of Chromatography B, 676 (1996) 141-146

 

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