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Fluticasone Impurity 7

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SZ CAT No:	SZ-F016055
CAS No	397864-41-4
Mol.F.	C31H30F2O8S
Mol.Wt.	600.6
Inv. Status	Custom Synthesis

Product Overview Description Technical Data

Chemical Name: (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-17-((furan-2-carbonyl)oxy)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic furan-2-carboxylic thioanhydride

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C(C1=CC=CO1)O[C@@]([C@]([C@@]2([H])C3)(C[C@H](O)[C@](F)([C@]4(C=C5)C)[C@@]2([H])C[C@H](F)C4=CC5=O)C)([C@@H]3C)C(SC(C6=CC=CO6)=O)=O

Characterisation of impurities in bulk drug batches of fluticasone propionate using directly coupled HPLC–NMR spectroscopy and HPLC–MS
Nisha Mistry a , Ismail M. Ismail b , Marco S. Smith c , Jeremy K. Nicholson d , John C. Lindon
Journal of Pharmaceutical and Biomedical Analysis 16 (1997) 697–705

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SynZeal will update these details as per new development or finding in product specification without further noticed.

Fluticasone Impurity 7

SZ CAT No:	SZ-F016055
CAS No	397864-41-4
Mol.F.	C31H30F2O8S
Mol.Wt.	600.6
Inv. Status	Custom Synthesis

Disclaimer

SynZeal will update these details as per new development or finding in product specification without further noticed.

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C(C1=CC=CO1)O[C@@]([C@]([C@@]2([H])C3)(C[C@H](O)[C@](F)([C@]4(C=C5)C)[C@@]2([H])C[C@H](F)C4=CC5=O)C)([C@@H]3C)C(SC(C6=CC=CO6)=O)=O

Fluticasone Impurity 7 is chemically (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-17-((furan-2-carbonyl)oxy)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic furan-2-carboxylic thioanhydride. Fluticasone Impurity 7 is supplied with detailed characterization data compliant with regulatory guideline. Fluticasone Impurity 7 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Fluticasone.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.