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Picture of Methotrexate EP Impurity H

Methotrexate EP Impurity H

SZ CAT No:SZ-M019009
CAS No67022-39-3
Mol.F.C21H24N8O5
Mol.Wt.468.5
Inv. StatusLimited Stock

Chemical Name: (2S)-2-[[4-[[(2,4-diaminopteridin-6-yl)methyl]methylamino]benzoyl]amino]-5-methoxy-5-oxopentanoic acid (as per EP) ; (S)-2-(4-{[(2,4-Diaminopteridin-6-yl)methyl](methyl)amino}benzamido)-5-methoxy-5-oxopentanoic acid (as per USP)

Synonym: Methotrexate 5-Methyl Ester (EP) ; Methotrexate USP Related Compound H

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: NC1=NC(N=CC(CN(C)C2=CC=C(C(N[C@@](CCC(OC)=O)(C(O)=O)[H])=O)C=C2)=N3)=C3C(N)=N1

Identification and Quantitation of Impurities in Methotrexate
dulal c. chatterji, altice g. frazier, and joseph f. gallell
Journal of Pharmaceutical Sciences Volume 67, Issue 5, May 1978, Pages 622-624
 
determination of methotrexate and its major metabolite, 7_hydroxymethotrexate, using capillary zone electrophoresis and laser-induced fluorescence detection
mark c. roach, philippe gozel and richard n. zare
Journal of Chromatography, 426 (1988) 129-140
 
Analytical methodologies for determination of methotrexate and its metabolites in pharmaceutical, biological and environmental samples
Forough Karami , Sara Ranjbar  , Younes Ghasemi , Manica Negahdaripour
Journal of Pharmaceutical Analysis 9 (2019) 373-391
 
Perspectives of Methotrexate-Based Radioagents for Application in Nuclear Medicine
Paweł Krzysztof Halik,* Przemysław Kozmin ́ ski, and Ewa Gniazdowska
Mol. Pharmaceutics 2021, 18, 1, 33–43
 

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