Naphazoline EP Impurity A

Determination of naphazoline HCl, pheniramine maleate and their official impurities in eye drops and biological fluid rabbit aqueous humor by a validated LC-DAD method
Khadiga M. Kelani,ab Maha A. Hegazy, a Amal M. Hassanb and Mahmoud A. Tantawy
RSC Adv., 2021,11, 7051-7058
 
A validated stability-indicating HPLC method for the simultaneous determination of pheniramine maleate and naphazoline hydrochloride in pharmaceutical formulations
Taomin Huang1*, Nianzu Chen1 , Donglei Wang1 , Yonghua Lai1 and Zhijuan Cao
 
Chemistry Central Journal 2014, 8:7 Spectrophotometric, chemometric and chromatographic determination of naphazoline hydrochloride and chlorpheniramine maleate in the presence of naphazoline hydrochloride alkaline degradation product
Nour el deen SayedMaha HegazyMohammed AbdelkawyRehab Abdelfatah
Bulletin of Faculty of Pharmacy, Cairo University Volume 51, Issue 1, June 2013, Pages 57-68

Naphazoline EP Impurity A is chemically N-(2-aminoethyl)-2-(naphthalen-1-yl)acetamide (naphthylacetylethylenediamine). It is also known as Naphazoline USP Related Compound A. Naphazoline EP Impurity A is supplied with detailed characterization data compliant with regulatory guideline. Naphazoline EP Impurity A can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Naphazoline.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.