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Chemical Name: (+)-(R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid ; (R)-(+)-Ofloxacin ; D-Ofloxacin ; Levofloxacin R-Isomer ;
Synonym: Ofloxacin R-Isomer
Shipping Temperature: Ambient
HSN Code: 38229010
Country of Origin: India
Smiles: O=C1C2=CC(F)=C(N3CCN(C)CC3)C(OC[C@H]4C)=C2N4C=C1C(O)=O
Ofloxacin R-Isomer is chemically (+)-(R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid ; (R)-(+)-Ofloxacin ; D-Ofloxacin ; Levofloxacin R-Isomer ; . It is also known as Ofloxacin R-Isomer. Ofloxacin R-Isomer is supplied with detailed characterization data compliant with regulatory guideline. Ofloxacin R-Isomer can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ofloxacin.
The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.
Use of various β-cyclodextrin derivatives as chiral selectors for the enantiomeric separation of ofloxacin and its five related substances by capillary electrophoresis
Bolin Zhu , Shuying Xu , Xingjie Guo , Lan Wei , Jia Yu , Tiejie Wang
J Sep Sci. 2017 Apr;40(8):1784-1795.
Stability Indicating Reversed-Phase High Performance Liquid Chromatography Method for Determination of Impurities in Ofloxacin Tablet Formulations
Bobba Venkateswara Reddy,1 Avvaru Praveen Kumar,2 Gosula Venkat Ram Reddy,1 Mohinish Sahai,1 Jadi Sreeramulu,1 and Jung Hag Park
Analytical Letters, 43: 2653–2662, 2010
Enantioseparation of ofloxacin and its four related substances with ligand exchange–micellar electrokinetic chromatography using copper(II)‐L‐isoleucine complex as chiral selector
Yongjing Liu Xiaoying Wang
Chirality Volume29, Issue8 August 2017 Pages 422-429
Multiple Response Optimization of a HPLC Method for the Determination of Enantiomeric Purity of S-Ofloxacin
Valliappan Kannappan & Sai Sandeep Mannemala
Chromatographia volume 77, pages1203–1211(2014)
