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Paclitaxel Impurity 42

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SZ CAT No:	SZ-P032053
CAS No	NA
Mol.F.	C50H73NO12Si2
Mol.Wt.	936.3
Inv. Status	Custom Synthesis

Product Overview Description Technical Data

Chemical Name: (αR,βS)-β-[Benzoylamino]-α-[[(1,1-dimethylethoxy)carbonyl]oxy]-benzenepropanoic Acid (2aS,3R,5S,5aS,7R,10S,12S,12aS,12bR)-2a,7-Bis(acetyloxy)-2a,3,4,5,5a,6,7,10,11,12,12a,12b-dodecahydro-3,12-dihydroxy-5a,9,13,13-tetramethyl-6-oxo-5-[(triethylsilyl)oxy]-8,12-methano-2H-cyclodec[cd]isobenzofuran-10-yl Ester;(2aS,2a1R,3R,5S,5aS,7R,10S,12S,12aS)-7-acetoxy-2a,3,12-trihydroxy-5a,9,13,13-tetramethyl-6-oxo-5-((triethylsilyl)oxy)-2a,2a1,3,4,5,5a,6,7,10,11,12,12a-dodecahydro-2H-8,12-methanocyclodeca[cd]isobenzofuran-10-yl (2R,3R)-3-benzamido-2-((tert-butyldimethylsilyl)oxy)-3-phenylpropanoate;

Synonym: 7-O-(Triethylsilyl)-2’-O-Tert-Butyl(dimethyl)silyl-4-Desacetyl-2-Debenzoyl-[2,4]oxol Paclitaxel

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O[C@H](C[C@@H]1O[Si](CC)(CC)CC)[C@]2(O)[C@@]([C@@]1(C3=O)C)([H])[C@H](OC2)[C@@](C4(C)C)(C[C@H](OC([C@H](O[Si](C(C)(C)C)(C)C)[C@@H](C5=CC=CC=C5)NC(C6=CC=CC=C6)=O)=O)C(C)=C4[C@H]3OC(C)=O)O

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SynZeal will update these details as per new development or finding in product specification without further noticed.

Paclitaxel Impurity 42

SZ CAT No:	SZ-P032053
CAS No	NA
Mol.F.	C50H73NO12Si2
Mol.Wt.	936.3
Inv. Status	Custom Synthesis

Disclaimer

SynZeal will update these details as per new development or finding in product specification without further noticed.

Synonym: 7-O-(Triethylsilyl)-2’-O-Tert-Butyl(dimethyl)silyl-4-Desacetyl-2-Debenzoyl-[2,4]oxol Paclitaxel

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O[C@H](C[C@@H]1O[Si](CC)(CC)CC)[C@]2(O)[C@@]([C@@]1(C3=O)C)([H])[C@H](OC2)[C@@](C4(C)C)(C[C@H](OC([C@H](O[Si](C(C)(C)C)(C)C)[C@@H](C5=CC=CC=C5)NC(C6=CC=CC=C6)=O)=O)C(C)=C4[C@H]3OC(C)=O)O

Paclitaxel Impurity 42 is chemically (αR,βS)-β-[Benzoylamino]-α-[[(1,1-dimethylethoxy)carbonyl]oxy]-benzenepropanoic Acid (2aS,3R,5S,5aS,7R,10S,12S,12aS,12bR)-2a,7-Bis(acetyloxy)-2a,3,4,5,5a,6,7,10,11,12,12a,12b-dodecahydro-3,12-dihydroxy-5a,9,13,13-tetramethyl-6-oxo-5-[(triethylsilyl)oxy]-8,12-methano-2H-cyclodec[cd]isobenzofuran-10-yl Ester;(2aS,2a1R,3R,5S,5aS,7R,10S,12S,12aS)-7-acetoxy-2a,3,12-trihydroxy-5a,9,13,13-tetramethyl-6-oxo-5-((triethylsilyl)oxy)-2a,2a1,3,4,5,5a,6,7,10,11,12,12a-dodecahydro-2H-8,12-methanocyclodeca[cd]isobenzofuran-10-yl (2R,3R)-3-benzamido-2-((tert-butyldimethylsilyl)oxy)-3-phenylpropanoate;. It is also known as 7-O-(Triethylsilyl)-2’-O-Tert-Butyl(dimethyl)silyl-4-Desacetyl-2-Debenzoyl-[2,4]oxol Paclitaxel. Paclitaxel Impurity 42 is supplied with detailed characterization data compliant with regulatory guideline. Paclitaxel Impurity 42 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Paclitaxel.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.