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Chemical Name: (2Z)-4-[(1S)-1-[[(1,1-dimethylethyl)amino]methyl]-2-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]ethoxy]-4-oxobut-2-enoic acid maleate (1:1) (as per EP); (S,Z)-4-({1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-yl}oxy)-4-oxobut-2- enoic acid maleate salt (1:1) (as per USP)
Synonym: Timolol USP Related Compound E
Shipping Temperature: Ambient
HSN Code: 38229010
Country of Origin: India
Smiles: O=C(/C=C\C(O)=O)O[C@@H](CNC(C)(C)C)COC1=NSN=C1N2CCOCC2.O=C(/C=C\C(O)=O)O
Timolol EP Impurity E (Maleate salt) is chemically (2Z)-4-[(1S)-1-[[(1,1-dimethylethyl)amino]methyl]-2-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]ethoxy]-4-oxobut-2-enoic acid maleate (1:1) (as per EP); (S,Z)-4-({1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]propan-2-yl}oxy)-4-oxobut-2- enoic acid maleate salt (1:1) (as per USP). It is also known as Timolol USP Related Compound E. Timolol EP Impurity E (Maleate salt) is supplied with detailed characterization data compliant with regulatory guideline. Timolol EP Impurity E (Maleate salt) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Timolol.
The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.
