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Picture of Abemaciclib D10

Abemaciclib D10

SZ CAT No:SZ-A077D02
CAS No2088650-71-7
Mol.F.C27H22D10F2N8
Mol.Wt.516.7
Inv. StatusCustom Synthesis

Chemical Name: N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-2-(methyl-d3)-1-(propan-2-yl-d7)-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: FC1=C2C(N(C(C([2H])([2H])[2H])=N2)C(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])=CC(C3=NC(NC4=CC=C(CN5CCN(CC)CC5)C=N4)=NC=C3F)=C1

Development and validation of a bioanalytical method for the quantification of the CDK4​/6 inhibitors abemaciclib, palbociclib, and ribociclib in human and mouse matrices using liquid chromatography-​tandem mass spectrometry
By Martinez-Chavez, Alejandra; Rosing, Hilde; Hillebrand, Michel; Tibben, Matthijs; Schinkel, Alfred H.; Beijnen, Jos H.
From Analytical and Bioanalytical Chemistry (2019), 411(20), 5331-5345

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