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Picture of Abemaciclib D7

Abemaciclib D7

SZ CAT No:SZ-A077D04
CAS NoNA
Mol.F.C27H25D7F2N8
Mol.Wt.513.7
Inv. StatusCustom Synthesis

Chemical Name: N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-2-methyl-1-(propan-2-yl-d7)-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: CC(N(C1=CC(C2=NC(NC3=CC=C(CN4CCN(CC)CC4)C=N3)=NC=C2F)=C5)C(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])=NC1=C5F

Development and validation of a bioanalytical method for the quantification of the CDK4​/6 inhibitors abemaciclib, palbociclib, and ribociclib in human and mouse matrices using liquid chromatography-​tandem mass spectrometry
By Martinez-Chavez, Alejandra; Rosing, Hilde; Hillebrand, Michel; Tibben, Matthijs; Schinkel, Alfred H.; Beijnen, Jos H.
From Analytical and Bioanalytical Chemistry (2019), 411(20), 5331-5345

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