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Hexanoyl Docetaxel Metabolites M1 and M3-d6 (Mixture of Diastereomers)

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SZ CAT No:	SZ-D031D05
CAS No	NA
Mol.F.	C49H55D6NO16
Mol.Wt.	926.0
Inv. Status	Custom Synthesis

Product Overview Description Technical Data

Chemical Name: (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3S)-2-(hexanoyloxy)-3-(4-hydroxy-5,5-bis(methyl-d3)-2-oxooxazolidin-3-yl)-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: CC(O[C@@]1([C@@H](C[C@@H]2O)OC1)[C@@]([C@@]2(C3=O)C)([H])[C@@H]([C@@](C4(C)C)(C[C@H](OC([C@@H]([C@@H](N5C(O)C(C([2H])([2H])[2H])(C([2H])([2H])[2H])OC5=O)C6=CC=CC=C6)OC(CCCCC)=O)=O)C(C)=C4[C@H]3O)O)OC(C7=CC=CC=C7)=O)=O

Development and validation of RP-HPLC method for simultaneous estimation of docetaxel and ritonavir in PLGA nanoparticles
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By Kumbhar, P. S.; Diwate, Sonali K.; Mali, U. G.; Shinde, T. U.; Disouza, J. I.; Manjappa, A. S.
From Annales Pharmaceutiques Francaises (2020), 78(5), 398-407

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Hexanoyl Docetaxel Metabolites M1 and M3-d6 (Mixture of Diastereomers)

SZ CAT No:	SZ-D031D05
CAS No	NA
Mol.F.	C49H55D6NO16
Mol.Wt.	926.0
Inv. Status	Custom Synthesis

Disclaimer

SynZeal will update these details as per new development or finding in product specification without further noticed.

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Hexanoyl Docetaxel Metabolites M1 and M3-d6 (Mixture of Diastereomers) is chemically (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3S)-2-(hexanoyloxy)-3-(4-hydroxy-5,5-bis(methyl-d3)-2-oxooxazolidin-3-yl)-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate. Hexanoyl Docetaxel Metabolites M1 and M3-d6 (Mixture of Diastereomers) is supplied with detailed characterization data compliant with regulatory guideline. Hexanoyl Docetaxel Metabolites M1 and M3-d6 (Mixture of Diastereomers) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Docetaxel.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.